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[细胞因子风暴的研究进展]

[Progress in research on cytokine storm].

作者信息

An N, Xianyu J P, Feng J F

机构信息

Department of Laboratory Medicine, Mianyang Central Hospital, Mianyang 621000, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Nov 6;54(11):1300-1304. doi: 10.3760/cma.j.cn112150-20200529-00799.

Abstract

Infectious disease is a kind of disease that can be transmitted between humans and animals. Respiratory infectious diseases are more likely to cause outbreaks through droplet transmission. Coronavirus has repeatedly caused global public health events. Initial symptoms of the infected patients were mild, and the onset of the disease was hidden, but some patients suddenly get worse in a short time, and eventually died due to multiple organ failure. Studies have found that cytokine storms caused by patients' excessive immune response was one of the important causes of death in the infected patients.

摘要

传染病是一种可在人与动物之间传播的疾病。呼吸道传染病更容易通过飞沫传播引发疫情。冠状病毒多次引发全球公共卫生事件。感染患者的初始症状较轻,发病隐匿,但部分患者在短时间内病情突然恶化,最终因多器官衰竭死亡。研究发现,患者过度免疫反应引发的细胞因子风暴是感染患者死亡的重要原因之一。

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