Pollock C A, Ibels L S
Royal North Shore Hospital, NSW.
Aust N Z J Med. 1987 Jun;17(3):321-5. doi: 10.1111/j.1445-5994.1987.tb01236.x.
Between 1977 and 1985, 5726 patients in Australia and New Zealand entered end stage renal failure programmes. Of these, 63 patients had renal failure due to systemic lupus erythematosus (a prevalence of 1.1% of patients entering renal replacement programmes). When compared with patients with other forms of glomerulonephritis, there was a female preponderance and a younger age distribution in patients with renal failure due to lupus nephritis. Integrated patient, dialysis, and transplant survival data showed that results in patients with renal failure due to lupus nephritis were comparable with those in patients with other forms of glomerulonephritis or in patients with renal failure due to any cause. Age at entry significantly affected survival, with significant differences being found in those patients under as opposed to over 50 years of age. Causes of death in patients with lupus nephritis were similar to those in patients with renal failure due to other causes. It is concluded that dialysis and transplantation are acceptable forms of treatment for patients with end stage renal failure due to systemic lupus erythematosus.
1977年至1985年间，澳大利亚和新西兰有5726名患者进入终末期肾衰竭项目。其中，63名患者因系统性红斑狼疮导致肾衰竭（占进入肾脏替代项目患者的1.1%）。与其他形式肾小球肾炎患者相比，狼疮性肾炎导致肾衰竭的患者中女性居多且年龄分布更年轻。综合患者、透析及移植存活数据显示，狼疮性肾炎导致肾衰竭患者的结果与其他形式肾小球肾炎患者或任何病因导致肾衰竭患者的结果相当。进入项目时的年龄显著影响存活率，50岁以下和50岁以上患者存在显著差异。狼疮性肾炎患者的死亡原因与其他病因导致肾衰竭患者的相似。得出的结论是，透析和移植是治疗系统性红斑狼疮导致终末期肾衰竭患者可接受的治疗方式。
