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EBV-related lymphoma after long-term daratumumab treatment: a case report.

作者信息

Verpoorte-Botden Ilse P G, Minnema Monique C, Raymakers Reinier A P

机构信息

Department of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Internal Medicine, Ziekenhuis Rivierenland Tiel, Tiel, The Netherlands.

出版信息

Blood Cancer J. 2020 Nov 4;10(11):113. doi: 10.1038/s41408-020-00379-y.

DOI:10.1038/s41408-020-00379-y
PMID:33149124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7642364/
Abstract
摘要

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Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open-label, phase 1/2 study.达雷妥尤单抗联合来那度胺和地塞米松治疗复发或复发/难治性多发性骨髓瘤患者的持久疗效和耐受性(GEN503):一项开放标签的1/2期研究的最终结果
Br J Haematol. 2019 Aug;186(3):e35-e39. doi: 10.1111/bjh.15879. Epub 2019 Mar 31.
2
Cytomegalovirus Reactivation in a Patient With Extensively Pretreated Multiple Myeloma During Daratumumab Treatment.达雷妥尤单抗治疗期间,一名接受过广泛预处理的多发性骨髓瘤患者出现巨细胞病毒再激活
Clin Lymphoma Myeloma Leuk. 2019 Jan;19(1):e9-e11. doi: 10.1016/j.clml.2018.10.002. Epub 2018 Oct 13.
3
Daratumumab plus lenalidomide and dexamethasone lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX.达雷妥尤单抗联合来那度胺和地塞米松 vs. 来那度胺和地塞米松治疗复发或难治性多发性骨髓瘤:POLLUX 更新分析。
Haematologica. 2018 Dec;103(12):2088-2096. doi: 10.3324/haematol.2018.194282. Epub 2018 Sep 20.
4
Severe cytomegalovirus enterocolitis developing following daratumumab exposure in three patients with multiple myeloma.3例多发性骨髓瘤患者在接受达雷妥尤单抗治疗后发生严重巨细胞病毒性小肠结肠炎。
Eur J Haematol. 2018 Aug 18. doi: 10.1111/ejh.13164.
5
Daratumumab, lenalidomide, and dexamethasone in East Asian patients with relapsed or refractory multiple myeloma: subgroup analyses of the phase 3 POLLUX study.达雷妥尤单抗、来那度胺和地塞米松治疗复发或难治性多发性骨髓瘤的东亚患者:III 期 POLLUX 研究的亚组分析。
Blood Cancer J. 2018 May 1;8(4):41. doi: 10.1038/s41408-018-0071-x.
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N Engl J Med. 2018 Feb 8;378(6):518-528. doi: 10.1056/NEJMoa1714678. Epub 2017 Dec 12.
7
Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma.达雷妥尤单抗、硼替佐米和地塞米松治疗多发性骨髓瘤。
N Engl J Med. 2016 Aug 25;375(8):754-66. doi: 10.1056/NEJMoa1606038.
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Blood. 2016 Oct 6;128(14):1821-1828. doi: 10.1182/blood-2016-07-726729. Epub 2016 Aug 16.
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Lenalidomide, Thalidomide, and Pomalidomide Reactivate the Epstein-Barr Virus Lytic Cycle through Phosphoinositide 3-Kinase Signaling and Ikaros Expression.来那度胺、沙利度胺和泊马度胺通过磷酸肌醇3激酶信号传导和IKAROS表达重新激活爱泼斯坦-巴尔病毒裂解周期。
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