Kharat Neetu, Waghmare Pallavi, Sarkar Mousumi, Nawal Sangeeta, Sahu Trilok, Dheeraj Munish
Department of Conservative Dentistry and Endodontics, RKDF Dental College & Research Center, Bhopal, Madhya Pradesh, India.
Department of Conservative Dentistry and Endodontics, Bhabha College of Dental Sciences, Bhopal, Madhya Pradesh, India.
J Pharm Bioallied Sci. 2020 Aug;12(Suppl 1):S233-S237. doi: 10.4103/jpbs.JPBS_68_20. Epub 2020 Aug 28.
Periapical lesions can be appreciated in the teeth that have underwent root canal treatment leading to more complications. Radiographic as well as histological evaluation is important for definitive diagnosis.
The aim of this study was to examine the histology of constant periapical radiolucent lesions that are associated with root canal treated teeth and also to find association between histological findings and radiographic size of lesion as well as existence or nonappearance of a radiopaque lamina.
The study included 60 incisors and canines allotted for apical microsurgery. Two observers studied the diameter of periapical radiolucent lesions and the existence or nonappearance of radiopaque lamina. During apical microsurgery, biopsy specimens were collected and after tissue processing oral pathologist examined the specimen under a light microscope. Histological features of the specimen were taken into consideration, and the diagnosis of abscess, cyst, granuloma, and scar tissue were given. Pearson's chi-square test was used to study the established relationship between histological diagnosis and lesion size.
Results indicated that 68.33% of lesions were granulomas, 23.33% were cysts, 5% were abscesses, and 3.33% were scar tissue.
According to histological results, most of the lesions in this study were granulomas, followed by cysts. Abscesses and scar tissues were rare.
根尖周病变可在已接受根管治疗的牙齿中出现,从而导致更多并发症。影像学及组织学评估对于明确诊断很重要。
本研究的目的是检查与根管治疗牙齿相关的持续性根尖周透射性病变的组织学情况,并找出组织学结果与病变的影像学大小以及阻射性骨板的存在与否之间的关联。
本研究纳入60颗分配用于根尖显微手术的切牙和尖牙。两名观察者研究根尖周透射性病变的直径以及阻射性骨板的存在与否。在根尖显微手术期间,采集活检标本,经过组织处理后,口腔病理学家在光学显微镜下检查标本。考虑标本的组织学特征,并给出脓肿、囊肿、肉芽肿和瘢痕组织的诊断。采用Pearson卡方检验研究组织学诊断与病变大小之间已确立的关系。
结果表明,68.33%的病变为肉芽肿,23.33%为囊肿,5%为脓肿,3.33%为瘢痕组织。
根据组织学结果,本研究中的大多数病变为肉芽肿,其次是囊肿。脓肿和瘢痕组织较少见。