Zeng Jing, Qu Pengpeng, Pang Qingsong, Wang Ping
Department of Gynecologic Oncology, Tianjin Central Hospital of Gynecology and Obstetrics, Affiliated Hospital of Nankai University, Tianjin 300100, People's Republic of China.
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, People's Republic of China.
Cancer Manag Res. 2020 Oct 29;12:10821-10828. doi: 10.2147/CMAR.S275378. eCollection 2020.
This study aims to measure the air-kerma rate of 192-Ir-HDR-afterloading source with an ionization chamber in air and a solid cylindrical phantom separately and to compare the dose calibration by the American Association of Physicists in Medicine (AAPM) Task Group TG-43U1 formalism with the Abacus treatment planning system (TPS).
The air-kerma rate of Ir source was measured by an ionization chamber in air and a solid cylindrical phantom separately. For the interesting point position (8cm, 90°), the values of the dose were calculated with the TG-43U1 formula and compared with data from the Abacus TPS with single and multiple dwell positions, respectively.
The air-kerma rate percentage deviations between the detector measurements in air and the source certificate were -1.28%, -0.91%, -0.71%, and 0.33% at the distances of 25cm, 50cm, 75cm, and 100cm, respectively. For the measurement in solid cylindrical phantom, the percent deviation from the air-kerma rate certificate was 1.85%. The percentage deviations of the dose calibration between Abacus TPS and TG-43U1 formalism at (8cm, 90°) were -2.30%, 1.76%, and 2.10% with different distances (between the dwell positions) of 0cm, 0.5cm, and 1cm, respectively.
The in-air technique was a new attempt for clinic routine measurement. Further studies are still necessary. As a treatment planning system, the Abacus TPS should apply the AAPM TG-43U1 formulism for the development required in the future.