Department of Pathology, Menoufia University, Shebein Elkom, Menoufia, 32511, Egypt.
F1000Res. 2020 Jun 25;9:645. doi: 10.12688/f1000research.23687.2. eCollection 2020.
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced as a separate entity by the World Health Organization in 2017 with strict inclusion and exclusion criteria. Most NIFTP cases have been reported in adults and few cases have been diagnosed in children. Here, we present a classic case of NIFTP affecting a 10-year old female child. We also review previous reports of NIFTP in children regarding size, focality, nodal metastasis, recurrence, type of operation and follow-up data. The present report adds a new case of NIFTP in the paediatric age group characterized by multifocality, absence of nodal invasion and indolent course until last follow-up, recommending less aggressive management.
非侵袭性滤泡性甲状腺肿瘤伴乳头状核特征(NIFTP)于 2017 年被世界卫生组织作为一个独立实体引入,具有严格的纳入和排除标准。大多数 NIFTP 病例发生在成年人中,很少有病例发生在儿童中。在此,我们报告了一个影响 10 岁女童的 NIFTP 经典病例。我们还回顾了之前关于儿童 NIFTP 的报告,包括大小、局灶性、淋巴结转移、复发、手术类型和随访数据。本报告增加了一个新的儿童 NIFTP 病例,其特征为多灶性、无淋巴结侵犯和惰性病程,直至最后一次随访,建议采用侵袭性较小的治疗方法。