Feder Idit, Duadi Hamootal, Fixler Dror
Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.
Biomed Opt Express. 2020 Sep 22;11(10):5760-5771. doi: 10.1364/BOE.401591. eCollection 2020 Oct 1.
In optical sensing, to reveal the chemical composition of tissues, the main challenge is isolating absorption from scattering. Most techniques use multiple wavelengths, which adds an error due to the optical pathlength differences. We suggest using a unique measurement angle for cylindrical tissues, the iso-pathlength (IPL) point, which depends on tissue geometry only (specifically the effective radius). We present a method for absorption assessment from a single wavelength at multiple measurement angles. The IPL point presented similar optical pathlengths for different tissues, both in simulation and experiments, hence it is optimal. Finally, measurements validated our proposed method.
在光学传感中，为了揭示组织的化学成分，主要挑战在于从散射中分离出吸收。大多数技术使用多个波长，这会由于光程长度差异而增加误差。我们建议对圆柱形组织使用一个独特的测量角度，即等光程（IPL）点，它仅取决于组织几何形状（具体为有效半径）。我们提出了一种在多个测量角度下从单一波长进行吸收评估的方法。在模拟和实验中，IPL点对于不同组织呈现出相似的光程长度，因此它是最优的。最后，测量结果验证了我们提出的方法。
