免疫学中的聚合物微珠

Polymer microbeads in immunology.

作者信息

Vĕtvicka V, Fornůsek L

机构信息

Oklahoma Medical Research Foundation, Oklahoma City.

出版信息

Biomaterials. 1987 Sep;8(5):341-5. doi: 10.1016/0142-9612(87)90003-2.

DOI:10.1016/0142-9612(87)90003-2

PMID:3315019

Abstract

Synthetic polymer microbeads have been studied extensively and the required properties, including monodispersity and size range 0.05-10 microns can best be achieved by radiation polymerization based on methacrylate derivatives. Fluorochrome-conjugated beads can be used for cell surface markers and simultaneously to study phagocytosis. The paper reviews some of these applications. Cell separation techniques are also described. Future possibilities for immunological and cell biology studies are discussed.

摘要

合成聚合物微珠已得到广泛研究，基于甲基丙烯酸酯衍生物的辐射聚合能够最好地实现所需特性，包括单分散性和0.05 - 10微米的尺寸范围。荧光染料偶联的微珠可用于细胞表面标志物研究，并同时用于吞噬作用研究。本文综述了其中一些应用。文中还描述了细胞分离技术。讨论了免疫和细胞生物学研究未来的可能性。