Department of Chemistry, University of Guilan, University Campus 2, Rasht, Iran.
Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Mol Divers. 2022 Feb;26(1):15-25. doi: 10.1007/s11030-020-10153-8. Epub 2020 Nov 5.
Tetrabutyl phosphonium sulfate ([TBP]SO), as novel room-temperature ionic liquid (RTIL), was synthesized by a simple cost-effective method, characterized by H, C, P NMR and FT-IR spectrophotometry. The newly prepared catalyst was used as an efficient catalyst in some four multicomponent reactions (4MCRs) e. g., to synthesis pyridazino[1,2-a]indazole, indazolo[2,1-b]phthalazine and pyrazolo[1,2-b]phthalazine. This green method has several advantages such as short reaction time, using simple methods to prepare catalysts and products, easy operation and high efficiency of products. In addition, the catalyst can be easily recovered and reused several times with reduced average activity.
硫酸四丁基膦 ([TBP]SO) 是一种新型的室温离子液体 (RTIL)，通过一种简单、经济高效的方法合成，通过 H、C、P NMR 和傅里叶变换红外光谱法进行了表征。新制备的催化剂可用作一些四组分反应 (4MCRs) 的高效催化剂，例如合成吡啶并[1,2-a]吲唑、吲唑并[2,1-b]酞嗪和吡唑并[1,2-b]酞嗪。这种绿色方法具有反应时间短、催化剂和产物的制备方法简单、操作方便、产物效率高等优点。此外，催化剂可回收并重复使用多次，平均活性降低。
