Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, People's Republic of China. University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Phys Med Biol. 2020 Nov 5;65(21):215024. doi: 10.1088/1361-6560/abb4bb.
Magneto-acousto-electrical tomography (MAET) is an imaging method coupled with sound field and magnetic field. The aim of this study is to present some novel experimental results of the mouse liver for the magneto-acousto-electrical tomography measured by two electrodes. The magnetic field in the space of 60 mm is about 300 mT which generate by two permanent magnets. A plane transducer with 2.25 MHz center frequency is utilized to generate acoustic waves inside the object. The signal is detected by two similar 1 mm copper foil electrodes. An amplifier is designed to receive the MAET signal, and the gain of the amplifier is adjusted to be 54 dB. The phantom used in this paper is a mouse liver surrounded by a gel phantom with the conductivity of 0.7 S m. The gel phantom with the conductivity of 0.7 S m is used to simulate the liver tumor, and the normal mouse liver is filled in the phantom. A series of the MAET signals are detected by the electrodes when the transducer is moved on a pre-set line route, then a B-scan image is realized. The experimental system can provide more information about the tumor and the results show that the MAET is sensitive enough for the potential clinical application of tumor in animal or human.
磁声电断层成像(MAET)是一种结合声场和磁场的成像方法。本研究的目的是介绍通过两个电极测量的老鼠肝脏的 MAET 的一些新的实验结果。空间内的磁场约为 60mm 为 300mT 由两个永磁体产生。一个具有 2.25MHz 中心频率的平面换能器用于在物体内部产生声波。信号由两个类似的 1mm 铜箔电极检测。设计了一个放大器来接收 MAET 信号,放大器的增益调整为 54dB。本文中使用的仿真是一个被凝胶仿体包围的老鼠肝脏,凝胶仿体的电导率为 0.7S/m。凝胶仿体的电导率为 0.7S/m 用于模拟肝肿瘤,正常的老鼠肝脏填充在仿体中。当换能器沿预设的线路移动时,通过电极检测一系列 MAET 信号,然后实现 B 扫描图像。实验系统可以提供有关肿瘤的更多信息,结果表明 MAET 对动物或人体肿瘤的潜在临床应用足够敏感。