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用于磁声电阻抗断层成像的乳腺组织模拟电声体模的研制。

Development of breast tissue-mimicking electrical and acoustic phantoms for magneto-acoustic electrical tomography.

作者信息

Zengin Reyhan, Gençer Nevzat Güneri

机构信息

Department of Biomedical Engineering, Inonu University, Malatya, Turkey.

Department of Electrical and Electronics Engineering, Middle East Technical University, Ankara, Turkey.

出版信息

Ann N Y Acad Sci. 2025 May;1547(1):192-203. doi: 10.1111/nyas.15338. Epub 2025 Apr 15.

Abstract

Magneto-acousto electrical tomography (MAET) is a novel medical imaging technique that relies on the difference in electrical properties between healthy and tumor tissues. To facilitate MAET experiments, this study proposes a comprehensive procedure for developing, characterizing, and preserving realistic breast tissue-mimicking phantoms. We developed nontoxic and inexpensive phantoms using sodium alginate, graphite powder, agar, propanediol, aluminum powder, glycine, and deionized water. The dielectric (conductivity and permittivity) and acoustic (speed of sound) properties of phantoms (breast fat, breast gland, and tumor) within the 1-8 MHz frequency range were measured to ensure their suitability for MAET experiments. In conclusion, this study presents a detailed methodology for the preparation, characterization, and preservation of realistic breast tissue-mimicking phantoms tailored for MAET experiments.

摘要

磁声电层析成像(MAET)是一种新型医学成像技术,它依赖于健康组织与肿瘤组织之间电学性质的差异。为便于开展MAET实验,本研究提出了一套全面的程序,用于开发、表征和保存逼真的乳腺组织模拟体模。我们使用海藻酸钠、石墨粉、琼脂、丙二醇、铝粉、甘氨酸和去离子水研制出了无毒且廉价的体模。测量了体模(乳腺脂肪、乳腺腺体和肿瘤)在1-8兆赫频率范围内的介电特性(电导率和电容率)和声学特性(声速),以确保其适用于MAET实验。总之,本研究给出了一套详细的方法,用于制备、表征和保存专门为MAET实验量身定制的逼真乳腺组织模拟体模。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c12d/12096805/6a5e7b845e20/NYAS-1547-192-g006.jpg

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