Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.
Contact Dermatitis. 2021 May;84(5):283-289. doi: 10.1111/cod.13736. Epub 2020 Nov 20.
It is recommended that patch test readings include a day (D)7 reading. Substitution of the D7 reading with a photo may be a valid option.
To compare the sensitivity of digital photos at D7 to clinical readings, to assess the number of positive reactions appearing at D7 only (late reactions), and after D7 only (delayed reactions).
Patients patch tested in six European clinics were instructed to forward photos of the patch test reactions to the respective clinics at D7 (before attending the clinic) and at D21. Only allergens in the baseline series or TRUE Test were included in the data analysis.
Two hundred ninety-three of 629 patients had a total of 599 positive reactions, with 6.3% occurring at D7 only. When substituting the D7 reading with a photo (90% submitted), 26.3% of late reactions were missed and nine false-positive reactions were found. Delayed reactions were detected in four patients at D21 (65.3% submitted).
Our data show that if the D7 reading is not performed, 6.3% of positive reactions from the baseline series would be missed, and if substituting the D7 reading by digital photo, 26.3% late reactions would be missed. Delayed reactions seemed rare.
建议斑贴试验的读片包括第 7 天（D7）的读片。用照片代替 D7 读片可能是一个有效的选择。
比较 D7 数字照片与临床读片的敏感性，评估仅在 D7 出现的阳性反应数量（迟发反应），以及仅在 D7 之后出现的阳性反应数量（延迟反应）。
在六个欧洲诊所接受斑贴试验的患者被指示在 D7（就诊前）和 D21 将斑贴试验反应的照片转发给各自的诊所。只有基础系列或 TRUE Test 中的变应原被包括在数据分析中。
在 629 名患者中的 293 名患者中共有 599 个阳性反应，其中 6.3%仅在 D7 出现。如果用照片代替 D7 读片（90%提交），则会错过 26.3%的迟发反应，并发现 9 个假阳性反应。在 21 天（4 名患者提交）时发现了 4 个延迟反应。
我们的数据表明，如果不进行 D7 读片，基础系列中 6.3%的阳性反应将被遗漏，如果用数字照片代替 D7 读片，26.3%的迟发反应将被遗漏。延迟反应似乎很少见。
