Department of Orthopedics, Huai An Hospital of Huai An City, No. 161, Zhenhuailou East Road, Huai'an District, Huai'an City, Jiangsu Province, 223200, China.
J Orthop Surg Res. 2020 Nov 5;15(1):509. doi: 10.1186/s13018-020-02035-4.
Postoperative delirium is a common psychiatric disorder among patients who undergo spinal surgery. The purpose of current meta-analysis was to assess the potential risk factors related to delirium in spinal surgery.
We searched the following databases: PubMed, EMBASE, the Cochrane Library, and Web of Science, from inception to July 2020. Two reviewers independently assessed the quality of the included studies using the previously described Newcastle-Ottawa Scale (NOS). We included spinal surgery patients who suffered with delirium or not. Stata 12.0 was used for meta-analysis.
Thirteen trial studies that met our inclusion criteria were incorporated into the meta-analysis. Postoperative delirium was associated with an increase of the duration of hospital stay (P = 0.044) and increased perioperative readmission rate (P = 0.013) and economic costs (P = 0.002). This meta-analysis demonstrates that there were twenty-two risk factors: general characteristic: old age, female patients, history of surgery, diabetes mellitus, hypertension; preoperative data: low hematocrit, low hemoglobin, low albumin, low sodium, depression; operative data: operating time, total blood loss; postoperative data: low sodium, low hemoglobin, low hematocrit, low albumin, fever, low potassium, blood sugar, and visual analog scale (VAS).
Delirium not only prolongs the length of hospital stay, but also increases readmission rate and the economic costs. Several risk factors including old age, female patients, history of surgery, diabetes mellitus, low hematocrit, low hemoglobin, low albumin, low sodium, depression; operative data: operating time, total blood loss, low sodium, low hemoglobin, low hematocrit, low albumin, fever, low potassium, blood sugar, and VAS were significant predictors for postoperative delirium after spinal surgery.
术后谵妄是脊柱手术后患者中常见的精神障碍。本次荟萃分析的目的是评估与脊柱手术相关的谵妄潜在风险因素。
我们检索了以下数据库：PubMed、EMBASE、Cochrane 图书馆和 Web of Science，从建库到 2020 年 7 月。两位评审员使用先前描述的纽卡斯尔-渥太华量表（NOS）独立评估纳入研究的质量。我们纳入了患有或不患有谵妄的脊柱手术患者。使用 Stata 12.0 进行荟萃分析。
符合纳入标准的 13 项试验研究被纳入荟萃分析。术后谵妄与住院时间延长（P=0.044）、围手术期再入院率增加（P=0.013）和经济成本增加（P=0.002）相关。本荟萃分析表明，有 22 个危险因素：一般特征：年龄较大、女性患者、手术史、糖尿病、高血压；术前数据：低血细胞比容、低血红蛋白、低白蛋白、低钠、抑郁；手术数据：手术时间、总失血量；术后数据：低钠、低血红蛋白、低血细胞比容、低白蛋白、发热、低钾、血糖和视觉模拟量表（VAS）。
谵妄不仅延长了住院时间，而且增加了再入院率和经济成本。几个危险因素，包括年龄较大、女性患者、手术史、糖尿病、低血细胞比容、低血红蛋白、低白蛋白、低钠、抑郁；手术数据：手术时间、总失血量、低钠、低血红蛋白、低血细胞比容、低白蛋白、发热、低钾、血糖和 VAS 是脊柱手术后发生术后谵妄的显著预测因素。
