University of Colorado, Academic Office 1, 12631 East 17th Avenue, Aurora, CO 802, USA.
Duke University Hospital, 203 Baker House, 201 Trent Drive, Durham, NC 27710, USA.
Clin Perinatol. 2020 Dec;47(4):835-846. doi: 10.1016/j.clp.2020.08.005. Epub 2020 Oct 16.
Understanding the pathophysiology, management, and prevention of emerging infectious diseases among pregnant women is imperative to achieve a successful response from the medical community. Ebola and Zika viruses represent infections with profound public health implications. In particular, Ebola virus is associated with high case fatality and pregnancy and neonatal loss rates, while Zika virus has been associated with multiple congenital anomalies; these features present critical clinical dilemmas for management of pregnant and reproductive aged women. The objective of this article is to summarize key background information and best practices for management of Ebola and Zika virus in pregnancy.
了解孕妇新发传染病的发病机制、管理和预防对于医疗界做出成功应对至关重要。埃博拉病毒和寨卡病毒是具有深远公共卫生意义的感染。特别是,埃博拉病毒与高病死率以及妊娠和新生儿损失率有关,而寨卡病毒与多种先天畸形有关;这些特征给孕妇和育龄妇女的管理带来了严峻的临床难题。本文的目的是总结埃博拉病毒和寨卡病毒妊娠管理的关键背景信息和最佳实践。