聚合酶链反应检测印度喀拉拉邦一家三级保健医院孕妇沙眼衣原体感染。
Detection of chlamydia trachomatis infection among the pregnant women attending a tertiary care hospital in Kerala - South India by polymerase chain reaction.
机构信息
Department of Microbiology, Azeezia Institute of Medical Sciences and Research, Kollam, Kerala, India.
Department of Microbiology, SR Medical College and Research Foundation, Thiruvananthapuram, Kerala, India.
出版信息
Indian J Med Microbiol. 2020 Jul-Dec;38(3 & 4):319-323. doi: 10.4103/ijmm.IJMM_19_429.
BACKGROUND
Chlamydia trachomatis infection is the most prevalent bacterial sexually transmitted infection and may influence pregnancy outcome.
AIMS AND OBJECTIVES
This study was conducted to assess Chlamydial infection during pregnancy by PCR.
MATERIALS AND METHODS
Study group consists of patients who are attending the antenatal clinics. Endocervical swabs were collected from 300 patients.
RESULTS
Off the 300 samples tested, 29 were positive as per PCR which used CT F : 5' CGT GTC GGC AAT CCT GCT GAT 3' and CT R : 5' GTC GAT AAC ATA GTC ACG ATA GTC 3'as the primers.
CONCLUSION
This suggests there is a prevalence of Chlamydia trachomatis in our population which is 10%. Hence, it should be noted as a significant public health problem especially among sexually active young women of child bearing age. Timely detection and prompt treatment of Chlamydial infection during pregnancy can eliminate its adverse outcomes.
背景
沙眼衣原体感染是最常见的细菌性性传播感染，可能会影响妊娠结局。
目的
本研究通过 PCR 评估妊娠期沙眼衣原体感染。
材料与方法
研究组由参加产前门诊的患者组成。从 300 名患者中采集宫颈拭子。
结果
根据使用 CT F：5' CGT GTC GGC AAT CCT GCT GAT 3' 和 CT R：5' GTC GAT AAC ATA GTC ACG ATA GTC 3'作为引物的 PCR 检测，300 个样本中有 29 个呈阳性。
结论
这表明我们人群中存在 10%的沙眼衣原体流行率。因此，应该将其视为一个重要的公共卫生问题，特别是在有生育能力的年轻性活跃女性中。及时检测和及时治疗妊娠期的衣原体感染可以消除其不良后果。
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