在一名经激发试验证实有轻度速发型反应的患者中成功进行地拉罗司重新激发试验并通过应对反应进行治疗：病例报告
Successful Deferasirox Rechallenge and Treating Through Reaction in a Patient with Challenge-Proven Mild Immediate Reaction: A Case Report.
作者信息
Sompornrattanaphan Mongkhon, Krikeerati Thanachit, Wongsa Chamard, Thongngarm Torpong, Yampayon Kittika
机构信息
Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
出版信息
J Asthma Allergy. 2020 Oct 30;13:557-561. doi: 10.2147/JAA.S271742. eCollection 2020.
This is the first report of successful deferasirox administration, using graded challenge and treating through, in a patient with mild immediate hypersensitivity reaction. Beginning with drug graded challenges could indicate the eliciting dose and reaction severity which are important for the management plan in the next step. This approach could be a safe shortcut in a stable patient with a mild reaction and a long avoidance period.
这是首例关于成功使用逐步激发并持续治疗的方法给予地拉罗司，治疗轻度速发型超敏反应患者的报告。从药物逐步激发开始可以确定引发剂量和反应严重程度，这对下一步的管理计划很重要。对于反应轻微且回避期较长的稳定患者，这种方法可能是一条安全的捷径。
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