持续正压通气对犬肝血流及肝内氧输送的影响。
Effects of continuous positive-pressure ventilation on hepatic blood flow and intrahepatic oxygen delivery in dogs.
作者信息
Sha M, Saito Y, Yokoyama K, Sawa T, Amaha K
机构信息
Department of Anesthesiology, Tokyo Medical and Dental University, Japan.
出版信息
Crit Care Med. 1987 Nov;15(11):1040-3. doi: 10.1097/00003246-198711000-00010.
The effect of mechanical ventilation with PEEP of 0, 10, and 20 cm H2O (continuous positive-pressure ventilation [CPPV]) on hepatic blood flow (HBF) and intrahepatic oxygen delivery was studied in 26 mongrel dogs anesthetized with fentanyl. Hepatic arterial and portal venous blood flow was measured by an electromagnetic flowmeter. CPPV caused a significant decrease in HBF, which was related to the PEEP level. A linear correlation was seen between HBF and cardiac output. Intrahepatic oxygen delivery decreased more than HBF and cardiac output. The reduced oxygen delivery was due mainly to the decrease in portal venous oxygen content.
在26只接受芬太尼麻醉的杂种犬中，研究了呼气末正压（PEEP）分别为0、10和20 cm H₂O的机械通气（持续正压通气[CPPV]）对肝血流量（HBF）和肝内氧输送的影响。通过电磁流量计测量肝动脉和门静脉血流量。CPPV导致HBF显著降低，这与PEEP水平有关。HBF与心输出量之间呈线性相关。肝内氧输送的下降幅度超过HBF和心输出量。氧输送减少主要是由于门静脉血氧含量降低所致。
Zotero 插件