Department of Cardiovascular Surgery, ICCV, Hospital Clínic, Barcelona, Spain.
Hemostasis and Hemotherapy Department, ICMHO, Hospital Clínic, Barcelona, Spain.
Interact Cardiovasc Thorac Surg. 2020 Dec 7;31(6):881-883. doi: 10.1093/icvts/ivaa196.
Heparin-induced thrombocytopaenia (HIT) complicates the management of patients in need for mechanical circulatory support awaiting heart transplantation. The limited available treatment options are fraught with complications and limitations in their applicability. We report on the combined use of therapeutic plasma exchange therapy and intravenous immunoglobulin, used in 3 consecutive heparin-induced thrombocytopaenia-positive patients on temporary mechanical circulatory support awaiting urgent heart transplant. This combined approach allowed us to use heparin safely.
肝素诱导的血小板减少症（HIT）使需要机械循环支持以等待心脏移植的患者的管理复杂化。有限的可用治疗选择存在并发症，并且在适用性方面存在限制。我们报告了在 3 例连续的肝素诱导的血小板减少症阳性、接受临时机械循环支持以等待紧急心脏移植的患者中联合使用治疗性血浆置换和静脉注射免疫球蛋白。这种联合方法使我们能够安全地使用肝素。
