Vildoso Priscila Stefani Vallejos, Pinho Jorge da Silva, Mattos Ana Paula Azevedo de, Rocha Gabrielle de Souza, Barroso Sergio Girão, Huguenin Grazielle Vilas Boas, Matos Andréa
Universidade Federal Fluminense.
Universidad Federal Fluminense.
Nutr Hosp. 2020 Dec 16;37(6):1209-1216. doi: 10.20960/nh.02962.
Introduction: resistant arterial hypertension (HAR) is associated with a high risk for cardiovascular events due to oxidative stress. Research has shown the beneficial effects of dietary antioxidants on cardiovascular health. Objective: to analyze and correlate the biochemical, anthropometric profile and intake of antioxidant micronutrients of patients with HAR. Material and methods: the patients underwent a biochemical assessment, and an anthropometric assessment to calculate body mass index (IMC), waist circumference (PCI), hip circumference (PCA), waist-to-hip ratio (ICC), and micronutrient intake assessment: vitamin A, vitamin C, vitamin E, selenium and zinc, estimated by a semi-quantitative food frequency questionnaire and 24-hour recall. The statistical analysis was performed using the SPSS Statistics 20 software. A p-value < 0.05 was considered significant. Results: sixty individuals with HAR were studied, with a mean age of 62.83 ± 10.73 years. Mean IMC was 31.01 ± 5.60 kg/m², PCI, 98.12 ± 15.04 cm, PCA, 110.55 ± 13.16 cm, and ICC, 0.879 ± 0.084. Regarding the biochemical profile, mean total colesterol was 187.65 ± 48.29 mg/dL, triglycerides, 136.38 ± 99.91 mg/dL; HDL-col, 49.00 ± 10.99 mg/dL; LDL-col, 112.01 ± 41.89 mg/dL; glucose, 105.37 ± 14.81 mg/dL, and glycated hemoglobin, 6.29 ± 1.76 %. The average daily intake of antioxidants was: vitamin A, 241.47 ± 191.87 µg/d; vitamin C, 147.02 ± 192.94 mg/d; vitamin E, 1.99 ± 1.82 mg/d; selenium, 36.80 ± 34.56 µg/d, and zinc, 99.91 ± 6.64 mg/d, where 91.38 %, 46.55 %, 93.10 %, 67.24 %, and 46.55 % of the sample were below the recommended intakes, respectively. Conclusion: inadequate antioxidant intake was observed in these patients with HAR, with a high prevalence of obesity, especially visceral adiposity and alterations in lipid profile, conditions that require a greater usage of these micronutrients. We suggest there is a need for dietary planning for these patients to improve their quality of life and their response to antihypertensive treatment.
顽固性动脉高血压（HAR）因氧化应激而与心血管事件的高风险相关。研究表明膳食抗氧化剂对心血管健康有益。目的：分析并关联HAR患者的生化指标、人体测量学特征以及抗氧化微量营养素的摄入量。材料与方法：对患者进行生化评估、人体测量学评估以计算体重指数（BMI）、腰围（WC）、臀围（HC）、腰臀比（WHR），以及微量营养素摄入量评估：通过半定量食物频率问卷和24小时膳食回顾法估算维生素A、维生素C、维生素E、硒和锌的摄入量。使用SPSS Statistics 20软件进行统计分析。p值<0.05被认为具有统计学意义。结果：研究了60例HAR患者，平均年龄为62.83±10.73岁。平均BMI为31.01±5.60kg/m²，WC为98.12±15.04cm，HC为110.55±13.16cm，WHR为0.879±0.084。关于生化指标，平均总胆固醇为187.65±48.29mg/dL，甘油三酯为136.38±99.91mg/dL；高密度脂蛋白胆固醇（HDL-C）为49.00±10.99mg/dL；低密度脂蛋白胆固醇（LDL-C）为112.01±41.89mg/dL；血糖为105.37±14.81mg/dL，糖化血红蛋白为6.29±1.76%。抗氧化剂的平均每日摄入量为：维生素A 241.47±191.87μg/d；维生素C 147.02±192.94mg/d；维生素E 1.99±1.82mg/d；硒36.80±34.56μg/d，锌99.91±6.64mg/d，其中分别有91.38%、46.55%、93.10%、67.24%和46.55%的样本低于推荐摄入量。结论：在这些HAR患者中观察到抗氧化剂摄入不足，肥胖患病率高，尤其是内脏脂肪过多以及血脂异常，这些情况需要更多地使用这些微量营养素。我们建议需要为这些患者制定饮食计划，以改善他们的生活质量以及他们对抗高血压治疗的反应。
