Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea .
Am J Dermatopathol. 2021 Apr 1;43(4):298-299. doi: 10.1097/DAD.0000000000001818.
Patients with eosinophilic pustular folliculitis (EPF), a sterile eosinophilic infiltration of hair follicles, often present with papulopustules that tend to form annular plaques. Histopathologic examination revealed eosinophilic infiltration around the pilosebaceous units and eosinophilic microabscess formation. Although the pathogenesis of EPF is unknown, T-helper type 2 immune responses were suggested to be important based on their stimulating effect on the sebaceous glands. Here, we report the first case of EPF associated with herpes zoster, indicating that herpes zoster and EPF are correlated with T-helper type 2 immune responses.
嗜酸性脓疱性毛囊炎(EPF)患者的毛囊存在无菌性嗜酸性粒细胞浸润,常表现为丘疹脓疱,易形成环状斑块。组织病理学检查显示毳毛皮脂腺单位周围有嗜酸性粒细胞浸润和嗜酸性微脓肿形成。尽管 EPF 的发病机制尚不清楚,但基于其对皮脂腺的刺激作用,提示辅助性 T 细胞 2 型免疫反应很重要。在此,我们报告首例与带状疱疹相关的 EPF,表明带状疱疹和 EPF 与辅助性 T 细胞 2 型免疫反应相关。