Xv Lulu, Wang Bin, Zhu Qing, Zhang Guoqiang
The First Hospital of Hebei Medical University, Shijiazhuang, China.
Clin Cosmet Investig Dermatol. 2023 Jul 7;16:1749-1752. doi: 10.2147/CCID.S415322. eCollection 2023.
This is a 58-year-old woman who has had itching on her right back for 10 days; a month ago she developed blisters on her right back with no apparent cause and pain, and was diagnosed with "herpes zoster". Erythema and blisters with itching reappeared 10 days ago on the right side of the back, where the original blisters had subsided. The histopathological manifestations of the lesions were: mild hyperkeratosis of the epidermis, pustules within the stratum corneum, irregular proliferation of the spinous layer, spongiosis, local destruction of the basal layer, infiltration of eosinophils, neutrophils, histiocytes and scattered plasma cells in the dermis and subcutis. According to the medical history, clinical manifestations and histopathology of the lesions, the diagnosis was Wolf's isotopic response after herpes zoster.
这是一位58岁女性，其右背部瘙痒10天；1个月前，她右背部无明显诱因出现水疱并伴有疼痛，被诊断为“带状疱疹”。10天前，原水疱消退处的右背部再次出现伴有瘙痒的红斑和水疱。病变的组织病理学表现为：表皮轻度角化过度，角质层内有脓疱，棘层不规则增生，海绵形成，基底层局部破坏，真皮和皮下组织有嗜酸性粒细胞、中性粒细胞、组织细胞浸润及散在浆细胞。根据病史、临床表现及病变的组织病理学检查，诊断为带状疱疹后Wolf同位反应。
