Division of Surgery, Department of Upper Gastrointestinal & Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.
Sheffield Medical School, University of Sheffield, Sheffield, United Kingdom.
PLoS One. 2020 Nov 6;15(11):e0241847. doi: 10.1371/journal.pone.0241847. eCollection 2020.
Laparoscopic vertical sleeve gastrectomy (LSG) is a popular bariatric procedure performed in Asia, as obesity continues to be on the rise in our population. A major problem faced is the development of de novo gastroesophageal reflux disease (GERD) after LSG, which can be chronic and debilitating. In this study, we aim to assess the relationship between the presence of small hiatal hernia (HH) and the development of postoperative GERD, as well as to explore the correlation between GERD symptoms after LSG and timing of meals. In doing so, we hope to gain a better understanding about the type of reflux that occurs after LSG and take a step closer towards effectively managing this difficult to treat condition.
We retrospectively reviewed data collected from patients who underwent LSG in our hospital from Dec 2008 to Dec 2016. All patients underwent preoperative upper GI endoscopy, during which the identification of hiatal hernia takes place. Patients' information and reflux symptoms are recorded using standardized questionnaires, which are administered preoperatively, and again during postoperative follow up visits.
Of the 255 patients, 125 patients (74%) developed de novo GERD within 6 months post-sleeve gastrectomy. The rate of de novo GERD was 57.1% in the group with HH, and 76.4% in the group without HH. Adjusted analysis showed no significant association between HH and GERD (RR = 0.682; 95% CI 0.419 to 1.111; P = 0.125). 88% of the patients who developed postoperative GERD reported postprandial symptoms occurring only after meals, and the remaining 12% of patients reported no correlation between the timing of GERD symptoms and meals.
There is no direct correlation between the presence of small hiatal hernia and GERD symptoms after LSG. Hence, the presence of a small sliding hiatal hernia should not be exclusion for sleeve gastrectomy. Electing not to perform concomitant hiatal hernia repair also does not appear to result in higher rates of postoperative or de novo GERD.
腹腔镜垂直袖状胃切除术(LSG)是亚洲流行的减肥手术,因为肥胖在我们的人群中持续上升。面临的一个主要问题是 LSG 后新发胃食管反流病(GERD)的发展,这种疾病可能是慢性的,使人虚弱。在这项研究中,我们旨在评估小裂孔疝(HH)的存在与术后 GERD 发展之间的关系,以及探讨 LSG 后 GERD 症状与用餐时间之间的相关性。通过这样做,我们希望更好地了解 LSG 后发生的反流类型,并朝着有效治疗这种难以治疗的疾病迈出一步。
我们回顾性地审查了 2008 年 12 月至 2016 年 12 月在我们医院接受 LSG 的患者的数据。所有患者均接受术前上消化道内镜检查,在此期间确定疝的存在。使用标准化问卷记录患者信息和反流症状,这些问卷在术前和术后随访期间进行。
在 255 名患者中,125 名(74%)在袖状胃切除术后 6 个月内新发 GERD。有 HH 的患者新发 GERD 的发生率为 57.1%,无 HH 的患者为 76.4%。调整分析显示 HH 与 GERD 之间无显著相关性(RR = 0.682;95%CI 0.419 至 1.111;P = 0.125)。88%发生术后 GERD 的患者报告餐后症状仅在餐后发生,其余 12%的患者报告 GERD 症状与用餐时间之间无相关性。
LSG 后小裂孔疝的存在与 GERD 症状之间没有直接的相关性。因此,小滑动裂孔疝的存在不应排除袖状胃切除术。选择不进行同时的裂孔疝修补术也不会导致术后或新发 GERD 的发生率更高。