Department of Biostatistics at Epidemiology, Biostatistics, and Prevention Institute, University of Zurich, Zurich, Switzerland.
Institute of Mathematics, University of Zurich, Zurich, Switzerland.
PLoS One. 2020 Nov 6;15(11):e0241897. doi: 10.1371/journal.pone.0241897. eCollection 2020.
Quality in medical research has recently been criticized for being low, especially in observational research. Methodology is increasingly difficult, but collaboration between clinical researchers and biostatisticians may improve research and reporting quality. The aim of this study is to quantify the value of a biostatistician in the team of authors.
Single-center, retrospective observational study following the STROBE reporting guidelines. We will systematically review all medical publications with biostatisticians from our center as co-authors or authors and review corresponding papers without biostatisticians from our center during the same time range. We will compare aspects of reporting quality, overall and for the three study types observational, randomized trial, and prognostic separately.
We anticipate that the results of the study will raise awareness of the importance of high methodological quality, as well as appropriate reporting quality in clinical research.
Our study will have a direct impact on our center by making each of us more aware of the reporting guidelines for various research designs. This in turn will enhance reporting quality in future research with our involvement. Our study will also raise awareness of the important role that biostatisticians play in the design and analysis of health research projects.
最近，医学研究的质量受到了批评，尤其是观察性研究。方法学越来越复杂，但临床研究人员和生物统计学家之间的合作可能会提高研究和报告的质量。本研究的目的是量化生物统计学家在作者团队中的价值。
遵循 STROBE 报告指南的单中心回顾性观察性研究。我们将系统地审查所有有我们中心的生物统计学家作为共同作者或作者的医学出版物，并在同一时间范围内审查没有我们中心的生物统计学家的相应论文。我们将比较报告质量的各个方面，包括整体和三种研究类型（观察性、随机试验和预后）的报告质量。
我们预计，这项研究的结果将提高人们对临床研究中高方法学质量以及适当报告质量的重要性的认识。
我们的研究将通过使我们每个人都更加了解各种研究设计的报告指南，直接影响我们中心。这反过来又将提高我们参与的未来研究的报告质量。我们的研究还将提高人们对生物统计学家在健康研究项目的设计和分析中所扮演的重要角色的认识。
