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扩大慢性阻塞性肺疾病患者出院后再入院指标

Expanding Post-Discharge Readmission Metrics in Patients with Chronic Obstructive Pulmonary Disease.

作者信息

Myers Laura C, Camargo Carlos, Escobar Gabriel, Liu Vincent X

机构信息

Division of Research, Kaiser Permanente Northern California, Oakland, California, United States.

The Permanente Medical Group, Oakland, California, United States.

出版信息

Chronic Obstr Pulm Dis. 2021 Jan;8(1):54-9. doi: 10.15326/jcopdf.2020.0160.

Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a common and costly reason for hospitalization and rehospitalization. The Hospital Readmissions Reduction Program penalizes hospitals for excess, non-elective, all-cause 30-day, inpatient rehospitalizations for COPD. We sought to determine how broadening the outcome definition would alter the numbers of patients being counted, specifically if observation stays and patients who died in the post-discharge period were included.

METHODS

We performed a retrospective cohort study of patients hospitalized for COPD between July 1, 2010 and December 31, 2017 in 21 hospitals in the Kaiser Permanente Northern California health care system. We classified encounters into 3 outcomes groups based on a 30-day post-discharge observation period: Group (1) non-elective, all-cause, inpatient rehospitalizations, which is the current metric; Group (2) composite outcome of Group 1 or all-cause mortality; and Group (3) composite outcome of Group 1 or non-elective, all-cause, observation rehospitalization. We used the Box-Cox method to find the transformation of the cumulative curves that resulted in the smallest mean standard error. We used the slope of the transformed curve against days to test for significant differences between pairs of cumulative density curves.

RESULTS

Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. The event rate for non-elective, all-cause, inpatient rehospitalizations was 17.1% (95% CI 10.4-26.5). The event rate for all-cause mortality was 4.7% (95% CI 3.1-7.7). The event rate for non-elective observation rehospitalizations was 3.9% (95% CI 1.7-7.0). The slope and standard error for Group 1 were 1.17 and 0.01, respectively, while the slope and standard error for Group 2 were 1.62 and 0.01, respectively (=0.02 comparing Groups 1 and 2). The slope and standard error for Group 3 were 1.45 and 0.01, respectively (=0.02 comparing Groups 1 and 3).

CONCLUSION

We show that adding outcomes such as mortality and observation rehospitalizations would change the counts of patients contributing to the Hospital Readmission Reduction Program penalty for COPD if the outcome were broadened. Including mortality or observation stays in the quality incentive program might incentivize hospitals and providers to prevent these events in addition to inpatient rehospitalizations.

摘要

背景

慢性阻塞性肺疾病(COPD)是住院和再住院的常见且费用高昂的原因。医院再入院减少计划会因慢性阻塞性肺疾病患者非选择性、全因性的30天住院再入院情况过多而对医院进行处罚。我们试图确定扩大结果定义将如何改变被统计的患者数量,特别是如果纳入观察期住院情况以及出院后死亡的患者。

方法

我们对2010年7月1日至2017年12月31日期间在北加利福尼亚凯撒医疗系统的21家医院因慢性阻塞性肺疾病住院的患者进行了一项回顾性队列研究。我们根据出院后30天的观察期将就诊情况分为3个结果组:组(1)非选择性、全因性住院再入院,这是当前的指标;组(2)组1的综合结果或全因性死亡;组(3)组1的综合结果或非选择性、全因性观察再入院。我们使用Box-Cox方法来找到使累积曲线转换后平均标准误差最小的转换方式。我们使用转换后曲线的斜率与天数来检验成对累积密度曲线之间的显著差异。

结果

在1384025次住院中,来自8097名患者的11304次就诊符合索引住院标准。非选择性、全因性住院再入院的发生率为17.1%(95%CI 10.4 - 26.5)。全因性死亡的发生率为4.7%(95%CI 3.1 - 7.7)。非选择性观察再入院的发生率为3.9%(95%CI 1.7 - 7.0)。组1的斜率和标准误差分别为1.17和0.01,而组2的斜率和标准误差分别为1.62和0.01(组1和组2比较,P = 0.02)。组3的斜率和标准误差分别为1.45和0.01(组1和组3比较,P = 0.02)。

结论

我们表明,如果扩大慢性阻塞性肺疾病的结果定义,增加死亡率和观察再入院等结果会改变导致医院再入院减少计划处罚的患者数量。在质量激励计划中纳入死亡率或观察期住院情况可能会激励医院和医疗服务提供者除了预防住院再入院外,还要预防这些事件。

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本文引用的文献

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Readmissions, Observation, and the Hospital Readmissions Reduction Program.再入院、观察和医院再入院率降低计划。
N Engl J Med. 2016 Apr 21;374(16):1543-51. doi: 10.1056/NEJMsa1513024. Epub 2016 Feb 24.

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