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准分子激光光动力角膜切削术(PTK)后的近视结果。

Myopic outcomes after excimer laser phototherapeutic keratectomy (PTK).

机构信息

Department of Ophthalmology, Rothschild Foundation, 29, rue Manin, 75019 Paris, France; Department of Ophthalmology, University Hospitals of Geneva, rue Alcide-Jentzer 22, 1205 Geneva, Switzerland.

Department of Ophthalmology, Rothschild Foundation, 29, rue Manin, 75019 Paris, France.

出版信息

J Fr Ophtalmol. 2021 Jan;44(1):35-40. doi: 10.1016/j.jfo.2020.03.024. Epub 2020 Nov 4.

Abstract

PURPOSE

To evaluate refractive outcomes following excimer laser phototherapeutic keratectomy (PTK).

METHODS

A retrospective non-randomized review of refractive outcomes of 146 consecutive eyes treated with excimer laser PTK at the Rothschild Foundation, Paris, France. Inclusion criteria were all patients undergoing PTK laser using a flying spot excimer laser system (Wavelight Allegretto, Alcon Surgical, Inc.) from October 2016 to June 2018. Exclusion criteria were incomplete data, irregular astigmatism and dystrophies of uncertain diagnosis. Preoperative diagnoses included recurrent corneal erosion syndrome without dystrophy and Cogan corneal dystrophies. The primary outcome measure was the change in spherical equivalent (SEQ) at M1 post PTK. The secondary outcome measure was the creation of a regression equation for predicting refractive outcomes after PTK, by analyzing the effect of ablation depth (AD) and optical zone (OZ) diameter.

RESULTS

Fifty-eight eyes of 54 patients were included. The mean OZ was 7.352 mm±0.622. The mean AD was 18.362μm±21.406. At M1 postoperatively, the mean SEQ was -2.485 D±2.628 and mean final SEQ was -1.052 D±1.260. Both OZ and AD were independent variables with significant effects on the final visual outcome. A regression equation for predicting refractive outcomes was established. No complications were observed.

CONCLUSION

The Wavelight flying spot excimer laser system produces myopic outcomes following PTK. Both OZ and AD are significant variables. A regression equation was created and may aid in prediction of refractive outcomes following PTK.

摘要

目的

评估准分子激光光动力角膜切削术(PTK)后的屈光结果。

方法

对法国巴黎 Rothschild 基金会使用飞点准分子激光系统(Alcon Surgical,Inc. 的 Wavelight Allegretto)治疗的 146 例连续眼的屈光结果进行回顾性非随机研究。纳入标准为所有接受 PTK 激光治疗的患者,纳入时间为 2016 年 10 月至 2018 年 6 月。排除标准为数据不完整、不规则散光和诊断不确定的营养不良。术前诊断包括无营养不良的复发性角膜糜烂综合征和 Cogan 角膜营养不良。主要观察指标为 PTK 后 M1 时球镜等效物(SEQ)的变化。次要观察指标为通过分析消融深度(AD)和光区(OZ)直径对预测 PTK 后屈光结果的影响,建立回归方程。

结果

纳入 54 例 58 只眼。平均 OZ 为 7.352mm±0.622。平均 AD 为 18.362μm±21.406。术后 M1 时平均 SEQ 为-2.485D±2.628,平均最终 SEQ 为-1.052D±1.260。OZ 和 AD 均为影响最终视觉结果的独立变量。建立了预测屈光结果的回归方程。未观察到并发症。

结论

Wavelight 飞点准分子激光系统可产生 PTK 后的近视结果。OZ 和 AD 均为显著变量。建立了回归方程,可帮助预测 PTK 后的屈光结果。

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