Department of Emergency Medicine, Mayo Clinic, Jacksonville, Florida.
Biostatistics Unit, Mayo Clinic, Jacksonville, Florida.
J Emerg Med. 2021 Feb;60(2):150-157. doi: 10.1016/j.jemermed.2020.10.005. Epub 2020 Nov 4.
Emergency department (ED) visits by lung transplant (LT) patients have not been well documented in the literature.
To analyze outcomes among LT recipients with ED visits, to better inform clinicians regarding evaluation and treatment.
This was a retrospective cohort study of LT patients at our ED (2015-2018). Demographics, transplant indication, laboratory studies, ED interventions, disposition, death, and revisit data were collected. Logistic regression models were used to identify univariable and multivariable predictors of ED revisit, intensive care unit (ICU) admission, or death.
For 505 ED visits among 160 LT recipients, respiratory-related concerns were most frequent (n = 152, 30.1%). Infection was the most common ED diagnosis (n = 101, 20.0%). Many patients were sent home from the ED (n = 235, 46.5%), and 31.3% (n = 158) returned to the ED within 30 days. Fourteen patients (2.8%) needed advanced airway measures. One patient died in the ED, and 18 died in the hospital. On multivariable analysis, more previous ED visits significantly increased the probability of 30-day ED revisit. Heart rate faster than 100 beats/min and systolic blood pressure < 90 mm Hg were significantly associated with ICU admission or death.
Infection should be prominent on the differential diagnosis for LT patients in the ED. A large proportion of patients were discharged from the ED, but a higher number of previous ED visits was most predictive of ED revisit within 30 days. Mortality rate was low in our study, but higher heart rate and lower systolic blood pressure were associated with ICU admission or death.
在文献中,肺移植(LT)患者的急诊就诊情况并未得到很好的记录。
分析 LT 接受者在急诊科就诊的结局,以便更好地为临床医生提供评估和治疗依据。
这是一项对我院急诊科 LT 患者(2015-2018 年)的回顾性队列研究。收集患者的人口统计学资料、移植指征、实验室检查结果、急诊科干预措施、转归、死亡和复诊数据。采用逻辑回归模型分析急诊科复诊、入住重症监护病房(ICU)或死亡的单变量和多变量预测因素。
在 160 例 LT 接受者的 505 次急诊科就诊中,最常见的是呼吸系统相关问题(n=152,30.1%)。最常见的急诊科诊断是感染(n=101,20.0%)。许多患者从急诊科出院(n=235,46.5%),其中 31.3%(n=158)在 30 天内再次就诊。14 例患者(2.8%)需要进行高级气道管理。1 例患者在急诊科死亡,18 例患者在医院死亡。多变量分析显示,就诊次数较多显著增加了 30 天内急诊科复诊的概率。心率大于 100 次/分钟和收缩压<90mmHg 与 ICU 入住或死亡显著相关。
在急诊科,LT 患者应重点考虑感染作为鉴别诊断。大多数患者从急诊科出院,但就诊次数较多是 30 天内再次就诊的最主要预测因素。本研究的死亡率较低,但较高的心率和较低的收缩压与 ICU 入住或死亡相关。