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非闭塞性肝动脉低灌注综合征及影像学表现:一项系统综述

Non-occlusive hepatic artery hypoperfusion syndrome and imaging findings: a systematic review.

作者信息

Durur Karakaya Afak, Çil Barbaros Erhan, Kanmaz Turan, Oğuzkurt Levent

机构信息

Department of Radiology, School of Medicine, Koç University, İstanbul, Turkey.

Liver Transplantation Center, School of Medicine, Koç University, İstanbul, Turkey.

出版信息

Abdom Radiol (NY). 2021 Jun;46(6):2467-2473. doi: 10.1007/s00261-020-02850-7. Epub 2020 Nov 6.

Abstract

Non-occlusive hepatic artery hypoperfusion syndrome (NHAHS), in other words, splenic steal, is a rare disorder that can arise following liver transplantation. After liver transplantation, its frequency has been defined as between 0.6 and 10.1%. The diversion of flow from hepatic to splenic arteries results in low perfused hepatic artery which causes elevated liver enzymes, hyperbilirubinemia, and graft dysfunction. This may result from a high resistance in the hepatic arteries, enlarged splenic arteries, a limited hepatic arterial flow due to high portal flow, or a discordance of the graft size and hepatic arterial flow. There may be a need for some prophylactic and/or posttransplant treatment procedures. We aimed to describe pre and post-treatment imaging findings of NHAHS.

摘要

非闭塞性肝动脉低灌注综合征(NHAHS),也就是脾盗血,是肝移植后可能出现的一种罕见病症。肝移植后,其发生率被界定为0.6%至10.1%。血流从肝动脉转向脾动脉会导致肝动脉灌注不足,进而引起肝酶升高、高胆红素血症和移植物功能障碍。这可能是由于肝动脉阻力高、脾动脉增粗、门静脉血流过高导致肝动脉血流受限,或者移植物大小与肝动脉血流不匹配所致。可能需要一些预防性和/或移植后的治疗措施。我们旨在描述NHAHS治疗前后的影像学表现。

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