Mothe Bhavani, Zafar Hasnain, Ahmed Shakil
Royal Liverpool and Broadgreen University Hospital NHS Trust, University Of Liverpool, UK.
Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2020 Oct;70(10):1799-1806. doi: 10.47391/JPMA.894.
Early rectal cancer management includes tumour stages TiS, T1 and some selected T2 lesions that undergo appropriate clinical pre-operatie evaluation. Local excision of these lesions with acceptable recurrence rate can be achieved through various transanal endoscopic techniques like transanal endoscopic microsurgery (TEM) and transanal minimal invasive surgery (TAMIS) that are superior to simple transanal excision (TAE). The current literature review was planned to present the oncological evaluation of local excision in the context of available evidence. An overview of perioperative adjuvant therapies employed along with local excision is presented, with an update on the latest trials.
早期直肠癌的治疗包括Tis、T1期肿瘤以及一些经过适当临床术前评估的特定T2期病变。通过各种经肛门内镜技术，如经肛门内镜显微手术（TEM）和经肛门微创手术（TAMIS），可以对这些病变进行局部切除，其复发率可接受，且优于单纯经肛门切除术（TAE）。本综述旨在根据现有证据，对局部切除的肿瘤学评估进行阐述。同时还将概述局部切除联合使用的围手术期辅助治疗方法，并介绍最新试验的进展情况。
