Usmani Sharjeel, Ahmed Najeeb, Muzaffar Samreen, Kandari Fareeda Al
Department of Nuclear Medicine, Kuwait Cancer Control Center (KCCC), Khaitan, Kuwait.
Department of Nuclear Medicine, Jack Brignall PET/CT Centre, Castle Hill Hosptial, Cottingham, United Kingdom.
J Pak Med Assoc. 2020 Oct;70(10):1867-1868.
18F- Sodium Fluoride (NaF) is an excellent bone imaging agent used for skeletal staging but can also be localized in extra osseous calcifying lesions. We report a case of a 38-year-old woman with breast carcinoma referred for 18F-NaF PET-CT to evaluate possible metastatic lesions. 18F-NaF PET-CT detected incidental focal soft tissue tracer uptake in the right cerebellum with no sign of calcification seen on CT images. Subsequent MRI show high intensity signal lesion confirming brain metastasis. Extra osseous 18F-NaF uptake may provide important diagnostic information that might alter patient management.
18F-氟化钠（NaF）是一种用于骨骼分期的优秀骨显像剂，但也可定位于骨外钙化病变。我们报告一例38岁乳腺癌女性患者，因18F-NaF PET-CT检查以评估可能的转移病变。18F-NaF PET-CT偶然发现右侧小脑有局灶性软组织示踪剂摄取，CT图像上未见钙化迹象。随后的MRI显示高强度信号病变，证实为脑转移。骨外18F-NaF摄取可能提供重要的诊断信息，从而可能改变患者的治疗方案。
