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三级转诊多学科诊所中糖尿病足溃疡的结局:一项加拿大回顾性研究。

Outcomes of Diabetic Foot Ulcers in a Tertiary Referral Interdisciplinary Clinic: A Retrospective Canadian Study.

机构信息

Hôtel-Dieu-de-Québec, Québec City, Québec, Canada.

Direction de la Recherche‒Recherche Clinique et Évaluative CHU de Québec-Université Laval, Québec City, Québec, Canada.

出版信息

Can J Diabetes. 2021 Apr;45(3):255-260. doi: 10.1016/j.jcjd.2020.09.004. Epub 2020 Sep 12.

Abstract

OBJECTIVES

The objectives of this work were to evaluate demographic data, healing rate, recurrence rate, amputation rate and death rate of patients with diabetic foot ulcers (DFUs) treated in a Québec outpatient diabetic foot ulcer multidisciplinary clinic. Another objective was to determine factors associated with higher ulcer recurrence.

METHODS

We conducted a retrospective cohort study of adults with diabetes with a DFU referred to a Québec City diabetic foot clinic between December 1, 2013 and May 1, 2019. The primary outcome was recurrence rate at 6 months after first ulcer healing. We also evaluated the recurrence rate at 12 months, mean and median time for ulcer healing, mean and median time before recurrence after first ulcer healing, amputation rate, mortality rate and factors associated with DFU recurrence.

RESULTS

Of the 85 patients included in the study, 26 (37.1%) and 36 (54.4%) had DFU recurrence at 6 months and 12 months, respectively, after first ulcer healing. Mean healing time from first consultation in the ulcer clinic was 19.64±21.02 weeks. Of the patients, 36.9% patients underwent lower limb amputation and 30.6% died during follow up. Both previous history of a DFU before first consultation and amputation after first DFU consultation were statistically significant risk factors for DFU recurrence at 12 months.

CONCLUSIONS

DFU recurrence was significantly higher in patients with a past history of DFU before the first one evaluated in the diabetic foot clinic and a previous history of amputation. Thus, systematic follow up should be done specifically with these patients.

摘要

目的

本研究旨在评估在魁北克门诊糖尿病足溃疡多学科诊所接受治疗的糖尿病足溃疡(DFU)患者的人口统计学数据、愈合率、复发率、截肢率和死亡率。另一目的是确定与更高溃疡复发率相关的因素。

方法

我们对 2013 年 12 月 1 日至 2019 年 5 月 1 日期间被转诊至魁北克市糖尿病足诊所的患有糖尿病的成年人进行了一项回顾性队列研究。主要结局是首次溃疡愈合后 6 个月的复发率。我们还评估了 12 个月的复发率、溃疡愈合的平均和中位数时间、首次溃疡愈合后复发的平均和中位数时间、截肢率、死亡率以及与 DFU 复发相关的因素。

结果

在纳入研究的 85 例患者中,分别有 26 例(37.1%)和 36 例(54.4%)在首次溃疡愈合后 6 个月和 12 个月时出现 DFU 复发。从首次在溃疡诊所就诊到愈合的平均时间为 19.64±21.02 周。36.9%的患者进行了下肢截肢,30.6%的患者在随访期间死亡。首次 DFU 就诊前有 DFU 病史和首次 DFU 就诊后截肢是 12 个月时 DFU 复发的统计学显著危险因素。

结论

在首次在糖尿病足诊所评估的 DFU 之前有 DFU 病史的患者和之前有截肢史的患者中,DFU 复发率显著更高。因此,应特别对这些患者进行系统随访。

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