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足部和踝关节双侧镜面对称性腱鞘巨细胞瘤:病例报告。

Bilateral Mirror-Symmetrical Giant Cell Tumor of the Tendon Sheath in the Foot and Ankle: A Case Report.

机构信息

Resident, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Associate Professor, Division of Orthopaedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

J Foot Ankle Surg. 2021 Jan-Feb;60(1):163-166. doi: 10.1053/j.jfas.2019.09.045. Epub 2020 Nov 5.

DOI:10.1053/j.jfas.2019.09.045
PMID:33162292
Abstract

Giant cell tumor of the tendon sheath is a slowly growing benign tumor. It usually arises from the tendon sheath and periarticular soft tissue of small joints. However, it may infrequently involve the large joints emerging around the knee, elbow, and hip joints. Giant cell tumor of the tibialis tendon sheath is rarely reported in the foot and ankle joint. Here, we report the first case in the medical literature of bilateral mirror-symmetrical giant cell tumor of the tendon sheath in the foot and ankle. A 12-year-old male presented with a bilateral and mirror-image mass on his ankles extending to the foot. It was painless but affected his gait and footwear. Staged complete resection was done first on the right then on the left side, with no recurrence after 1 year. The role of genes can be argued for this presentation and giant cell tumor's etiology, owing to the bilateralism and mirror-image presentation. Studies are needed to explore this genetic aspect and its role in management.

摘要

腱鞘巨细胞瘤是一种生长缓慢的良性肿瘤。它通常起源于小关节的腱鞘和关节周围软组织。然而,它也可能偶尔累及膝关节、肘关节和髋关节周围的大关节。发生在足部和踝关节的腱鞘巨细胞瘤极为罕见。在此,我们报告首例足部和踝关节双侧镜面对称性腱鞘巨细胞瘤。一名 12 岁男性因双侧踝关节延伸至足部的镜像肿块就诊。肿块无疼痛,但影响其步态和穿鞋。首先对右侧进行分期性完全切除,然后对左侧进行切除,1 年后无复发。鉴于双侧性和镜像表现,基因在这种表现和巨细胞瘤的病因中可能发挥作用。需要研究来探讨这一遗传方面及其在治疗中的作用。

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