Shen Carl, Nath Siddharth
Division of Ophthalmology, Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
MD/PhD Program, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Am J Ophthalmol Case Rep. 2020 Oct 28;20:100986. doi: 10.1016/j.ajoc.2020.100986. eCollection 2020 Dec.
To describe a case of nontraumatic subperiosteal orbital hemorrhage (NTSOH) in a laboring patient with gestational immune thrombocytopenic purpura.
A 28-year-old G3P2 laboring patient was urgently evaluated by our ophthalmology unit after she developed sudden onset left eye proptosis, headache, and diplopia in the final hour of pushing. The patient's platelet count was markedly decreased at 45,000 and subsequent work-up established a diagnosis of gestational immune thrombocytopenic purpura. On examination, visual acuity was 20/25 bilaterally and there was a minus two restriction in upgaze in the left eye and a left hypotropia in primary position. Computed tomography demonstrated an elliptical, hyperdense collection at the left orbital roof consistent with NTSOH. The patient was deemed clinically stable through serial examinations and symptoms resolved with conservative management.
NTSOH is a rare, potentially sight-threatening condition that requires timely ophthalmological evaluation. To our knowledge, this is the first report in the literature of NTSOH in a laboring patient with gestational immune thrombocytopenic purpura. Consideration of the possibility of NTSOH as a complication in this population may allow for appropriate diagnosis, monitoring, and treatment when indicated.
描述一例患有妊娠期免疫性血小板减少性紫癜的临产患者发生非创伤性骨膜下眼眶出血(NTSOH)的病例。
一名28岁、孕3产2的临产患者在用力分娩的最后一小时突然出现左眼突出、头痛和复视,随后由我们的眼科团队进行了紧急评估。患者的血小板计数显著降低,为45,000,随后的检查确诊为妊娠期免疫性血小板减少性紫癜。检查发现,患者双眼视力均为20/25,左眼上视受限2度,原在位时有左眼低位。计算机断层扫描显示左眼眶顶有一个椭圆形的高密度影像,符合非创伤性骨膜下眼眶出血。通过系列检查,患者被判定临床状况稳定,症状经保守治疗后缓解。
非创伤性骨膜下眼眶出血是一种罕见的、可能威胁视力的疾病,需要及时进行眼科评估。据我们所知,这是文献中首例关于患有妊娠期免疫性血小板减少性紫癜的临产患者发生非创伤性骨膜下眼眶出血的报告。考虑到该人群发生非创伤性骨膜下眼眶出血作为并发症的可能性,在有指征时可进行适当的诊断、监测和治疗。