Children's Hospital of Michigan, Detroit, MI, USA.
Pathology, Children's Hospital of Michigan, Detroit, MI, USA.
Fetal Pediatr Pathol. 2022 Jun;41(3):493-498. doi: 10.1080/15513815.2020.1843575. Epub 2020 Nov 9.
Fibroepithelial polyps of the anus have been described as mucosal hypertrophy in response to chronic irritation or tissue damage. Lesions usually remain small and mostly present in elderly adults with local disease. An otherwise healthy 15-year-old male presented with a giant pedunculated mass projecting out of the anal verge that enlarged over 2 years, causing discomfort. Upon surgical excision and histologic examination, the mass resembled a fibroepithelial polyp with numerous dilated lymphatics. While literature describes the spectrum of pathology possible in such lesions, often consisting of a mixture of stromal and epithelial components, dilated lymphatics are less common. This giant anal fibroepithelial polyp characterized by edematous stroma and numerous dilated lymphatics is consistent with lymphangioma. To our knowledge, this presentation is novel in this age group with no underlying risk factors.
肛门纤维上皮息肉被描述为黏膜对慢性刺激或组织损伤的增生反应。病变通常较小，主要见于有局部疾病的老年患者。一位无其他异常的 15 岁男性出现了一个从肛门边缘突出的巨大带蒂肿块，2 年来逐渐增大，引起不适。经手术切除和组织学检查，肿块类似于纤维上皮息肉，其中有许多扩张的淋巴管。虽然文献描述了此类病变中可能存在的病理谱，通常由间质和上皮成分的混合物组成，但扩张的淋巴管并不常见。这个巨大的肛门纤维上皮息肉的特点是基质水肿和许多扩张的淋巴管，符合淋巴管瘤的特征。据我们所知，这种在无潜在危险因素的情况下发生于该年龄组的表现较为罕见。
