Ingram M, Shelden C H, Jacques S, Skillen R G, Bradley W G, Techy G B, Freshwater D B, Abts R M, Rand R W
Experimental and Clinical Immunotherapy Laboratory, Huntington Medical Research Institutes, Pasadena, CA 91101.
J Biol Response Mod. 1987 Oct;6(5):489-98.
An immunotherapy protocol based on intracranial implantation of stimulated, autologous lymphocytes into the tumor bed following surgical debulking of malignant glioma is described. Phase I clinical trials in human patients are now in progress. Preliminary data representing the first 39 patients treated are presented briefly.