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哪些因素可能区分强迫症患者中终身有自杀未遂行为者和有自杀意念者?

Which factors may differentiate lifetime suicide attempters from ideators in obsessive-compulsive disorder patients?

作者信息

Memis Cagdas Oyku, Dogan Bilge, Sevincok Doga, Tunagur Tolga, Memis Seda Derici, Sevincok Levent

机构信息

Department of Psychiatry, Adnan Menderes University School of Medicine, Aydin, Turkey.

Department of Child and Adolescent Psychiatry, Adnan Menderes University School of Medicine, Aydin, Turkey.

出版信息

Indian J Psychiatry. 2020 Jul-Aug;62(4):392-399. doi: 10.4103/psychiatry.IndianJPsychiatry_540_19. Epub 2020 Jul 27.

DOI:10.4103/psychiatry.IndianJPsychiatry_540_19
PMID:33165338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7597723/
Abstract

BACKGROUND

The causes underlying suicidal behaviour in patients with obsessive-compulsive (OCD) are not fully understood.

AIM

In this study, we examined whether lifetime suicide attempt (SA), and suicide ideation (SI) was associated with affective temperaments, impulsivity, childhood traumatic events or separation anxiety.

METHODS

We compared OCD patients with lifetime SA (Group 1; =25), lifetime suicide ideation (SI) (Group 2; =62), and without lifetime SI and SA (Group 3; =73) through Beck Scale for Suicidal Ideation (BSSI), Childhood Trauma Questionnaire Questionnaire (CTQ-SF), Separation Anxiety Symptom Inventory (SASI), Baratt Impulsiveness Scale (BIS-11), Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A), and Beck Depression Inventory (BDI).

RESULTS

Post hoc tests showed that educational level was significantly lower in Group 1 than in both Group 2 and 3. Childhood abuse were significantly higher in attempters than ideators, and non-suicidal patients. The depressive, cyclothymic, and anxious temperaments were significantly higher in attempters and ideators compared to control subjects. The aggressive obsessions (=0.002), childhood abuse history (=0.009), lifetime major depression (=0.017), and lower educational levels (=0.006) strongly predicted the increased risk of lifetime SA, compared to non-suicidal patients. Childhood abuse (=0.022) was the most significant predictor of lifetime SA in OCD.

CONCLUSION

We suggested that childhood abuse history emerged as the most significant variable that distinguished lifetime attempters from only ideators in OCD patients.

摘要

背景

强迫症(OCD)患者自杀行为的潜在原因尚未完全明确。

目的

在本研究中,我们探讨了终生自杀未遂(SA)和自杀意念(SI)是否与情感气质、冲动性、童年创伤事件或分离焦虑相关。

方法

我们通过贝克自杀意念量表(BSSI)、儿童创伤问卷简版(CTQ-SF)、分离焦虑症状量表(SASI)、巴拉特冲动性量表(BIS-11)、孟菲斯、比萨、巴黎和圣地亚哥气质评估量表(TEMPS-A)以及贝克抑郁量表(BDI),对有终生自杀未遂经历的强迫症患者(第1组;n = 25)、有终生自杀意念的患者(第2组;n = 62)和无终生自杀意念及自杀未遂经历的患者(第3组;n = 73)进行了比较。

结果

事后检验显示,第1组患者的教育水平显著低于第2组和第3组。有自杀未遂经历的患者童年期受虐情况显著高于有自杀意念的患者和无自杀行为的患者。与对照组相比,有自杀未遂经历和有自杀意念的患者抑郁、环性心境和焦虑气质显著更高。与无自杀行为的患者相比,攻击性强迫观念(P = 0.002)、童年期受虐史(P = 0.009)、终生重度抑郁(P = 0.017)以及较低的教育水平(P = 0.006)强烈预示着终生自杀未遂风险增加。童年期受虐(P = 0.022)是强迫症患者终生自杀未遂的最显著预测因素。

结论

我们认为,童年期受虐史是区分强迫症患者中终生有自杀未遂经历者和仅有自杀意念者的最显著变量。

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Depress Anxiety. 2019 Jul;36(7):586-595. doi: 10.1002/da.22907. Epub 2019 May 8.
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