Department of Analytical Chemistry and Food Technology, Environmental Sciences Institute (ICAM), University of Castilla-La Mancha, Avda. Carlos III s/n, 45071, Toledo, Spain.
Department of Analytical Chemistry and Food Technology, Faculty of Chemical Sciences and Technologies, University of Castilla-La Mancha, Avda. Camilo José Cela s/n, 13071, Ciudad Real, Spain.
Talanta. 2021 Jan 15;222:121513. doi: 10.1016/j.talanta.2020.121513. Epub 2020 Aug 14.
An analytical methodology based on asymmetric flow field flow fractionation hyphenated to inductively coupled plasma mass spectrometry (AF4-ICP-MS) has been developed for monitoring citrate coated platinum nanoparticles (PtNPs) of different sizes (5, 30, and 50 nm) in water samples. Several factors have been optimized, such as carrier composition, AF4 separation program, focusing step or cross flow values. Under the optimum conditions, PtNPs can be fractionated in about 30 min in a single run with quantitative recoveries of the membrane (100 ± 7%, n = 5). The optimized method has been successfully applied to study transformations, not only in size but also surface modifications, of PtNPs in synthetic and natural water samples over time. The effect of organic matter was specifically studied, and it was found to be a critical parameter. The analytical strategy followed in this work can be very useful to develop further environmental studies involving PtNPs.
基于不对称流场流分离与电感耦合等离子体质谱联用的分析方法（AF4-ICP-MS）已被开发用于监测不同粒径（5nm、30nm 和 50nm）的柠檬酸包覆铂纳米粒子（PtNPs）在水样中的情况。对多种因素进行了优化，如载体组成、AF4 分离程序、聚焦步骤或交叉流值。在最佳条件下，PtNPs 可以在单次运行中约 30 分钟内进行分离，并且膜的定量回收率为 100±7%（n=5）。该优化方法已成功应用于研究合成和天然水样中 PtNPs 的转化，不仅是粒径的转化，还有表面修饰的转化。特别研究了有机物的影响，发现其是一个关键参数。本工作中采用的分析策略对于进一步开展涉及 PtNPs 的环境研究可能非常有用。
