N.D. Zelinsky Institute of Organic Chemistry, RAS, Leninskii Prosp., Moscow 119991, Russia.
Int J Mol Sci. 2020 Nov 5;21(21):8284. doi: 10.3390/ijms21218284.
High-resolution electrospray mass spectra (MS and MS/MS CID) of positive ions of a series of protonated, ammoniated, and metallated molecules of cyclic -substituted oligo-β-(1→6)-D-glucosamines differing in cycle size and -acyl substituents were registered and interpreted. It was shown that the main type of fragmentation is a cleavage of glycosidic bonds of a cycle, and in some cases fragmentation of amide side chains is possible. If labile fragments in substituents (e.g., carbohydrate chains) are present, a decay of the cycle and an elimination of labile fragments are of comparable possibility. It was found that in some cases rearrangements with loss of an internal carbohydrate residue (IRL), or an internal part of a side chain, are feasible.
已注册并解释了一系列环取代寡-β-（1→6）-D-葡糖胺的质子化、氨化和金属化分子的正离子的高分辨电喷雾质谱（MS 和 MS/MS CID），这些分子的环大小和-酰基取代基不同。结果表明，主要的断裂类型是环的糖苷键的断裂，在某些情况下，酰胺侧链的断裂也是可能的。如果取代基中存在不稳定的片段（例如，碳水化合物链），则环的衰减和不稳定片段的消除具有相当的可能性。研究发现，在某些情况下，带有内部碳水化合物残基（IRL）或内部侧链部分损失的重排是可行的。
