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胸腰椎爆裂骨折保守治疗失败的预测因素。

Predictors of the failure of conservative treatment in patients with a thoracolumbar burst fracture.

机构信息

Department of Neurosurgery, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Kermanshah University of Medical Sciences, Imam Reza Hospital, Kermanshah, Iran.

出版信息

J Orthop Surg Res. 2020 Nov 10;15(1):514. doi: 10.1186/s13018-020-02044-3.

Abstract

BACKGROUND

There is a controversy about the management of patients with a thoracolumbar burst fracture. Despite the success of the conservative treatment in most of the cases, some patients failed the conservative treatment. The present study aimed to evaluate risk factors for the need for surgery during the follow-up period in these patients.

METHODS

We retrospectively evaluated 67 patients with a traumatic thoracolumbar burst fracture who managed conservatively at our center between May 2014 and May 2019. Suggested variables as potential risk factors for the failure of conservative treatment including age, gender, body mass index (BMI), smoking, diabetes, vertebral body compression rate (VBCR), percentage of anterior height compression (PAHC), Cobb angle, interpedicular distance (IPD), canal compromise, and pain intensity as visual analog scale (VAS) were compared between patients with successful conservative treatment and those with failure of non-operative management.

RESULTS

There were 41 males (61.2%) and 26 females (38.8%) with the mean follow-up time of 15.52 ± 5.30 months. Overall, 51 patients (76.1%) successfully completed conservative treatment. However, 16 cases (23.9%) failed the non-operative management. According to the binary logistic regression analysis, only age (risk ratio [RR], 2.21; 95% confidence interval [95%], 1.78-2.64; P = 0.019) and IPD (RR 1.97; 95% CI 1.61-2.33; P = 0.005) were the independent risk factors for the failure of the non-operative management.

CONCLUSIONS

Our results showed that older patients and those with greater interpedicular distance are at a higher risk for failure of the conservative treatment. As a result, a closer follow-up should be considered for them.

摘要

背景

对于胸腰椎爆裂骨折患者的治疗存在争议。尽管大多数病例的保守治疗都取得了成功,但仍有一些患者保守治疗失败。本研究旨在评估这些患者在随访期间需要手术的相关风险因素。

方法

我们回顾性评估了 2014 年 5 月至 2019 年 5 月期间在我院接受保守治疗的 67 例创伤性胸腰椎爆裂骨折患者。对可能导致保守治疗失败的潜在风险因素(年龄、性别、体重指数(BMI)、吸烟、糖尿病、椎体压缩率(VBCR)、前柱高度压缩百分比(PAHC)、Cobb 角、椎弓根间距(IPD)、椎管狭窄和疼痛强度作为视觉模拟评分(VAS))进行比较,比较成功接受保守治疗和非手术治疗失败的患者。

结果

患者中男性 41 例(61.2%),女性 26 例(38.8%),平均随访时间 15.52±5.30 个月。总体而言,51 例(76.1%)患者成功完成保守治疗,16 例(23.9%)患者非手术治疗失败。根据二元逻辑回归分析,仅年龄(风险比[RR],2.21;95%置信区间[95%CI],1.78-2.64;P=0.019)和 IPD(RR,1.97;95%CI,1.61-2.33;P=0.005)是保守治疗失败的独立风险因素。

结论

我们的研究结果表明,年龄较大和椎弓根间距较大的患者保守治疗失败的风险更高。因此,应对他们进行更密切的随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e3/7654172/54d5f7f1a241/13018_2020_2044_Fig1_HTML.jpg

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