Department of Internal Medicine, University of Toledo, Toledo, Ohio, USA
Department of Internal Medicine, Karachi Medical and Dental College, Karachi, Pakistan.
BMJ Case Rep. 2020 Nov 9;13(11):e237173. doi: 10.1136/bcr-2020-237173.
Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources can be either endogenous (Cushing's syndrome) or exogenous (Anabolic steroid abuse). Cardiovascular complications due to excess glucocorticoid includes hypertension, left ventricular hypertrophy, myocardial infarction, and heart failure. Although anabolic steroid-induced cardiomyopathy is a well-recognised phenomenon, endogenous corticosteroid-induced cardiomyopathy and heart failure are rarely reported sequelae of glucocorticoid excess in the body. We report a glucocorticoid-induced dilated cardiomyopathy in a 26-year-old African-American man with cushingoid features and symptomatic heart failure.
糖皮质激素过多是心血管不良事件的一个未被充分认识的原因。其来源可以是内源性的（库欣综合征）或外源性的（滥用合成代谢类固醇）。由于糖皮质激素过多引起的心血管并发症包括高血压、左心室肥厚、心肌梗死和心力衰竭。虽然合成代谢类固醇诱导的心肌病是一种公认的现象，但内源性皮质类固醇诱导的心肌病和心力衰竭是糖皮质激素过多在体内罕见的后遗症。我们报告了一例 26 岁的非洲裔美国男性发生的糖皮质激素诱导的扩张型心肌病，其表现为库欣样特征和有症状的心衰。
