Department of Neurosurgery, YueYang Second People's Hospital, Hunan, China.
Department of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Childs Nerv Syst. 2021 Jul;37(7):2387-2390. doi: 10.1007/s00381-020-04965-0. Epub 2020 Nov 9.
Pediatric craniopharyngioma is typically characterized by cystic changes and calcifications. It can grow from the suprasellar area to the posterior fossa (4%). This work reports that it is very rare for craniopharyngioma to grow from the suprasellar area to or beyond the level of the foramen magnum. Twelve patients with this disease have undergone one or several microsurgeries, and the microsurgical approaches are different. Among them, two cases died, and most of the remaining patients had certain complications such as endocrine dysfunction, nerve palsy, and subdural effusion. We treated two patients whose tumors had grown to the level of the foramen magnum, one of which reached C2 levels. Both cases were treated with a neuroendoscopy. There were no deaths and no complications. Our cases are the longest follow-up of this type of craniopharyngioma.
小儿颅咽管瘤的典型特征是囊性变和钙化。它可以从鞍上区生长到后颅窝（4%）。本研究报告称，颅咽管瘤从鞍上区生长到或超过枕骨大孔水平非常罕见。12 名患者接受了一次或多次微创手术，手术入路不同。其中 2 例死亡，其余大多数患者存在内分泌功能障碍、神经麻痹和硬膜下积液等并发症。我们治疗了 2 例肿瘤生长至枕骨大孔水平的患者，其中 1 例达到 C2 水平。这两例均采用神经内镜治疗。无死亡病例，无并发症发生。我们的病例是此类颅咽管瘤随访时间最长的病例。
