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前后对照队列研究评估分粹性消融二氧化碳激光治疗儿童手部瘢痕的疗效。

Before-after cohort study to assess the efficacy of fractional ablative carbon dioxide laser treatment of pediatric hand scars.

机构信息

Department of Hand and Plastic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, People's Republic of China.

Department of Aesthetic, Plastic and Burn Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, 250021, People's Republic of China.

出版信息

Lasers Med Sci. 2021 Sep;36(7):1455-1460. doi: 10.1007/s10103-020-03186-w. Epub 2020 Nov 9.

DOI:10.1007/s10103-020-03186-w
PMID:33169274
Abstract

The purpose of this study is to investigate the efficacy of fractional ablative carbon dioxide laser (AFXL) surgery in patients with pediatric hand scars. This study enrolled hand scar patients who received treatment in our hospital between May 2018 and April 2019. Patients were assigned to undergo AFXL surgery based on their personal intents and condition, whereas the fractional laser was used for stiffness and abnormal texture. Outcomes were as follows: hand function was evaluated using the Michigan hand outcomes questionnaire; scar condition was evaluated using the Vancouver scar scale and UNC4P scar scale. Total 30 pediatric patients (mean age, 11.4 years) were eligible for the study and laser-treated scars were significantly improved in Michigan hand outcomes questionnaire from 52.30 ± 6.14 to 66.91 ± 6.43 (p < 0.001). Provider-rated Vancouver scar scale dropped from 8.80 ± 2.75 to 6.73 ± 2.52 (p < 0.001). Patient-reported UNC4P scar scale declined from7.07 ± 2.02 to 4.73 ± 1.31 (p < 0.001). AFXL surgery can significantly improve hand function and appearance of pediatric hand scars, suggesting its advantages over traditional methods of operative intervention.

摘要

本研究旨在探讨分段式非剥脱性二氧化碳激光(AFXL)手术治疗小儿手部瘢痕的疗效。本研究纳入了 2018 年 5 月至 2019 年 4 月在我院接受治疗的手部瘢痕患者。患者根据个人意愿和病情选择接受 AFXL 手术,而分段式激光则用于治疗手部瘢痕的僵硬和异常纹理。研究结果如下:手部功能采用密歇根手功能问卷进行评估;瘢痕状况采用温哥华瘢痕量表和 UNC4P 瘢痕量表进行评估。共有 30 名符合条件的小儿患者(平均年龄 11.4 岁)接受了激光治疗,密歇根手功能问卷评分从 52.30±6.14 分提高到 66.91±6.43 分(p<0.001)。温哥华瘢痕量表的提供者评分从 8.80±2.75 分降至 6.73±2.52 分(p<0.001)。患者报告的 UNC4P 瘢痕量表评分从 7.07±2.02 分降至 4.73±1.31 分(p<0.001)。AFXL 手术可显著改善小儿手部瘢痕的手部功能和外观,优于传统手术干预方法。

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