Luzikov V N
Mol Biol (Mosk). 1987 Sep-Oct;21(5):1157-71.
The paper summarizes data on the nature of signals (mainly amino acid sequences) determining the intracellular movement of newly formed polypeptide chains: their secretion, incorporation into the cytoplasmic or endoplasmic reticular membranes, into different compartments of mitochondria and chloroplasts. Some information is given about the polypeptide transport into the nucleus and microbodies (glyoxysomes, peroxysomes, glucosomes). The intracellular movement of polypeptides is supposed to be proteolytically controlled.
本文总结了关于决定新形成的多肽链细胞内移动的信号(主要是氨基酸序列)性质的数据:它们的分泌、并入细胞质或内质网膜、进入线粒体和叶绿体的不同区室。还给出了一些关于多肽转运到细胞核和微体(乙醛酸循环体、过氧化物酶体、糖体)的信息。多肽的细胞内移动被认为是受蛋白水解控制的。