Pla Begoña, Arranz Alfonso, Knott Carolina, Sampedro Miguel, Jiménez Sara, Hernando Iñigo, Marazuela Monica
Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
J Endocr Soc. 2020 Oct 13;4(12):bvaa149. doi: 10.1210/jendso/bvaa149. eCollection 2020 Dec 1.
To examine the impact of the lockdown caused by the COVID-19 pandemic on both the glycemic control and the daily habits of a group of patients with type 1 diabetes mellitus (T1DM) using flash continuous glucose monitoring devices (flash CGMs).
Retrospective analysis based on all the information gathered in virtual consultations from a cohort of 50 adult patients with T1DM with follow-up at our site. We compared their CGM metrics during lockdown with their own previous data before the pandemic occurred, as well as the potential psychological and therapeutic changes.
We observed a reduction of average glucose values: 160.26 ± 22.55 mg/dL vs 150 ± 20.96 mg/dL, = .0009; estimated glycosylated hemoglobin: 7.21 ± 0.78% vs 6.83 ± 0.71%, = .0005; glucose management indicator 7.15 ± 0.57% vs 6.88 ± 0.49%; = .0003, and glycemic variability: 40.74 ± 6.66 vs 36.43 ± 6.09 < .0001. Time in range showed an improvement: 57.46 ± 11.85% vs a 65.76 ± 12.09%, < .0001, without an increase in percentage of time in hypoglycemia.
COVID-19 lockdown was associated with an improvement in glycemic control in patients with T1DM using CGMs.
使用闪光连续血糖监测设备（闪光CGM），研究2019冠状病毒病（COVID-19）大流行导致的封锁对一组1型糖尿病（T1DM）患者血糖控制和日常习惯的影响。
基于在我们机构接受随访的50例成年T1DM患者队列的虚拟会诊中收集的所有信息进行回顾性分析。我们将他们在封锁期间的CGM指标与其在大流行发生前自己的先前数据进行比较，以及潜在的心理和治疗变化。
我们观察到平均血糖值降低：160.26±22.55mg/dL对150±20.96mg/dL，P = 0.0009；估计糖化血红蛋白：7.21±0.78%对6.83±0.71%，P = 0.0005；血糖管理指标7.15±0.57%对6.88±0.49%；P = 0.0003，以及血糖变异性：40.74±6.66对36.43±6.09，P < 0.0001。血糖达标时间有所改善：57.46±11.85%对65.76±12.09%，P < 0.0001，低血糖时间百分比未增加。
COVID-19封锁与使用CGM的T1DM患者血糖控制改善相关。
