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溃疡性结肠炎基础上发生的结肠穿孔致肠黏膜 T 细胞淋巴瘤 1 例报告

Intestinal T-cell lymphoma presenting as colonic perforation in the setting of ulcerative colitis: a case report.

机构信息

Department of Surgery, The Wollongong Hospital, Loftus Street, Wollongong, New South Wales, 2500, Australia.

出版信息

Clin J Gastroenterol. 2021 Feb;14(1):176-180. doi: 10.1007/s12328-020-01279-1. Epub 2020 Nov 10.

Abstract

The intestinal T-cell lymphomas are a rare group of lymphatic malignancies arising from the gastrointestinal tract. They frequently manifest with non-specific clinical and radiographic findings that may mimic several other disease processes. The most common subtype is linked with refractory coeliac disease and commonly affects the small intestine. We report a case where the diagnosis was uncovered endoscopically in a patient presenting with colonic perforation on a background of long-standing ulcerative colitis. Surgical source control was required prior to considering chemotherapy, which is the usual treatment option in lymphatic malignancies. The case highlights the importance endoscopic evaluation in inflammatory conditions of the colon.

摘要

肠 T 细胞淋巴瘤是一组罕见的起源于胃肠道的淋巴恶性肿瘤。它们常表现为非特异性的临床和影像学表现,可能模仿几种其他疾病过程。最常见的亚型与难治性乳糜泻有关,通常影响小肠。我们报告了一例病例,该病例在溃疡性结肠炎长期背景下发生结肠穿孔的患者中经内镜检查发现。在考虑化疗之前,需要进行手术源控制,化疗是淋巴恶性肿瘤的常用治疗选择。该病例强调了在结肠炎症性疾病中进行内镜评估的重要性。

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