Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany
Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.
Thorax. 2021 Feb;76(2):201-204. doi: 10.1136/thoraxjnl-2020-216088. Epub 2020 Nov 11.
Various forms of diffuse parenchymal lung disease have been proposed as potential consequences of severe COVID‑19. We describe the clinical, radiological and histological findings of patients with COVID‑19-associated acute respiratory distress syndrome who later developed severe organising pneumonia including longitudinal follow-up. Our findings may have important implications for the therapeutic modalities in the late-phase of severe COVID‑19 and might partially explain why a subgroup of COVID‑19 patients benefits from systemic corticosteroids.
各种形式的弥漫性肺实质疾病被认为是严重 COVID-19 的潜在后果。我们描述了 COVID-19 相关急性呼吸窘迫综合征患者的临床、放射学和组织学发现,这些患者后来发展为严重的机化性肺炎,包括纵向随访。我们的发现可能对严重 COVID-19 后期的治疗方式具有重要意义,并可能部分解释为什么 COVID-19 患者的亚组从全身皮质类固醇治疗中获益。