CNRS, Laboratoire Modélisation et Simulation Multi Echelle, Créteil Cedex, France.
Université Polytechnique des Hauts de France, Laboratoire d'Automatique, de Mécanique et d'informatique Industrielles et Humaines, Valenciennes, France.
J Prosthodont Res. 2021 Aug 21;65(3):421-427. doi: 10.2186/jpr.JPR_D_20_00052. Epub 2020 Nov 12.
Purpose Quantitative ultrasound (QUS) and resonance frequency analyses (RFA) are promising methods to assess the stability of dental implants. The aim of this in vivo preclinical study is to compare the results obtained with these two techniques with the bone-implant contact (BIC) ratio, which is the gold standard to assess dental implant stability.Methods Twenty-two identical dental implants were inserted in the tibia and femur of 12 rabbits, which were sacrificed after different healing durations (0, 4, 8 and 13 weeks). For each implant, the ultrasonic indicator (UI) and the implant stability quotient (ISQ) were retrieved just before the animal sacrifice using the QUS and RFA techniques, respectively. Histomorphometric analyses were carried out to estimate the bone-implant contact ratio.Results UI values were found to be better correlated to BIC values (R²=0.47) compared to ISQ values (R²=0.39 for measurements in one direction and R²=0.18 for the other direction), which were shown to be dependent on the direction of measurements. Errors realized on the UI were around 3.3 times lower to the ones realized on the ISQ.Conclusions QUS provide a better estimation of dental implant stability compared to RFA. This study paves the way for the future clinical development of a medical device aiming at assessing dental implant stability in a patient-specific manner. Clinical studies should confirm these results in the future.
定量超声(QUS)和共振频率分析(RFA)是评估牙种植体稳定性的有前途的方法。本临床前体内研究的目的是比较这两种技术与骨-种植体接触(BIC)比的结果,BIC 比是评估牙种植体稳定性的金标准。
22 个相同的牙种植体被植入 12 只兔子的胫骨和股骨中,在不同的愈合时间(0、4、8 和 13 周)后处死这些兔子。对于每个种植体,在动物牺牲前使用 QUS 和 RFA 技术分别获得超声指标(UI)和种植体稳定性指数(ISQ)。进行组织形态计量学分析以估计骨-种植体接触比。
与 ISQ 值(一个方向的 R²=0.39,另一个方向的 R²=0.18)相比,UI 值与 BIC 值的相关性更好(R²=0.47),ISQ 值被证明取决于测量方向。在 UI 上的误差比在 ISQ 上的误差低约 3.3 倍。
与 RFA 相比,QUS 提供了对牙种植体稳定性的更好估计。这项研究为未来以患者特异性方式评估牙种植体稳定性的医疗设备的临床发展铺平了道路。未来的临床研究应该证实这些结果。