Jaroma H J, Ritsilä V A
Department of Surgery, Kuopio University Central Hospital, Finland.
Scand J Plast Reconstr Surg Hand Surg. 1987;21(2):175-81. doi: 10.3109/02844318709078097.
The osteo-chondrogenic potential of free periosteal grafts was investigated within the knee joint in 26 rabbits aged four to six weeks. A total of 36 knee joints were operated on. The grafts were stripped from the medial side of the right tibia and sutured on the articular surface of the patella, from which the cartilage had been totally excised to the subchondral bone. In 16 knees the graft was sutured with the cambium layer towards the subchondral bone and in eight knees the fibrous layer faced the bone. In the control group of twelve knees the patellar articular cartilages were excised and no periosteal transplant was grafted to the patellar articular surface. In the transplantation group cartilage formation could be seen already one week after the operation. There were no marked differences between the series with the cambium layer facing the subchondral bone or the group with the fibrous layer facing the bone. At 20 weeks the hypertrophied cartilage had thinned and resembled normal joint cartilage. In the control group the histological picture resembled osteoarthritis.
对26只4至6周龄兔子的膝关节内游离骨膜移植物的骨软骨生成潜力进行了研究。总共对36个膝关节进行了手术。将移植物从右胫骨内侧剥离，缝合到髌骨的关节表面，髌骨的软骨已被完全切除至软骨下骨。在16个膝关节中，移植物以形成层朝向软骨下骨进行缝合，在8个膝关节中，纤维层朝向骨。在12个膝关节的对照组中，切除髌骨关节软骨，未将骨膜移植物移植到髌骨关节表面。在移植组中，术后1周即可见软骨形成。形成层朝向软骨下骨的系列与纤维层朝向骨的组之间没有明显差异。在20周时，肥大的软骨变薄，类似于正常关节软骨。在对照组中，组织学图像类似于骨关节炎。
