J Am Podiatr Med Assoc. 2020 Sep 1;110(5). doi: 10.7547/18-809.
Morton's neuromas are abnormalities of the common digital nerve branch located between the lesser metatarsal heads. Historically, interdigital (Morton's) neuromas have been characterized as being most common in the third interspace and in females. The principal investigator observed Morton's neuromas commonly in the second and third interspaces in both sexes. To our knowledge, no literature exists to evaluate Morton's neuroma location with a focus on each sex independently. The present study evaluates Morton's neuroma interspace location and whether there is a variation by sex.
In this retrospective study, 582 deidentified magnetic resonance imaging reports with a diagnosis code for Morton's neuroma were evaluated for patients scanned from January 2, 2015, through April 19, 2016. Incomplete records and those with radiologist findings inconsistent with Morton's neuroma were eliminated. For the remaining 379 patients, data were collected on sex, laterality, history of trauma, plantar plate tear, age, and interspace location. Special focus was given to second and third interspace Morton's neuromas. Data were evaluated using the Pearson χ2 and independent-samples Mann-Whitney U tests, with P < .05 indicating statistical significance.
No statistically significant distribution between sex and second and third interspace Morton's neuromas was noted. Right vs left foot, age, and history of trauma did not vary statistically significantly between sexes. There was a statistically significant difference between the presence of plantar plate tears between sexes. Male patients with Morton's neuromas were found to have a higher rate of plantar plate tears (P = .01).
This study found that there were no statistically significant differences between sexes and Morton's neuromas location, laterality, or age.
Morton 神经瘤是位于小跖骨头部之间的常见指神经分支的异常。历史上，指间（Morton）神经瘤的特征是在第三间隙最常见，且多见于女性。主要研究者观察到男性和女性的第二和第三间隙中常见 Morton 神经瘤。据我们所知，目前尚无文献评估每个性别独立的 Morton 神经瘤位置。本研究评估 Morton 神经瘤间隙位置，以及是否存在性别差异。
在这项回顾性研究中，评估了 2015 年 1 月 2 日至 2016 年 4 月 19 日期间扫描的 582 份经鉴定的无身份信息的磁共振成像报告，这些报告均有 Morton 神经瘤的诊断代码。排除了记录不完整和放射科医生发现与 Morton 神经瘤不一致的报告。对于其余 379 名患者，收集了性别、侧别、创伤史、跖板撕裂、年龄和间隙位置的数据。特别关注第二和第三间隙 Morton 神经瘤。使用 Pearson χ2 和独立样本 Mann-Whitney U 检验评估数据，P<.05 表示有统计学意义。
未观察到性别与第二和第三间隙 Morton 神经瘤之间存在统计学上的分布差异。右足与左足、年龄和创伤史在性别之间没有统计学上的显著差异。性别之间的跖板撕裂存在统计学上的显著差异。患有 Morton 神经瘤的男性患者发现跖板撕裂的发生率更高（P=0.01）。
本研究发现性别与 Morton 神经瘤的位置、侧别或年龄之间没有统计学上的显著差异。
