Zheng Jie, Yu Jingjing, Zhou Tao
Department of Breast Cancer Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Division of Gland Sugery, The Third Hospital of Xingtai, Xingtai, China.
J Int Med Res. 2020 Nov;48(11):300060520969304. doi: 10.1177/0300060520969304.
Ductal carcinoma in situ (DCIS) with microinvasion (DCIS-MI) is defined as the extension of cancer cells beyond the basement membrane into adjacent tissue with no focus larger than 1 mm or a maximum diameter of less than 1 mm for multiple invasive foci. DCIS-MI constitutes approximately 1% of all breast cancer cases and 5% to 10% of cases of DCIS. The current literature is controversial concerning the clinical prognostic features and management of DCIS-MI. This narrative review described recently reported literature regarding the characteristics, diagnosis, treatment, and prognosis of DCIS-MI.
伴有微浸润的导管原位癌(DCIS-MI)定义为癌细胞突破基底膜延伸至邻近组织,且最大浸润灶直径不超过1毫米,若存在多个浸润灶,则其最大直径之和小于1毫米。DCIS-MI约占所有乳腺癌病例的1%,占DCIS病例的5%至10%。目前关于DCIS-MI的临床预后特征及治疗方法的文献存在争议。本叙述性综述介绍了近期报道的有关DCIS-MI的特征、诊断、治疗及预后的文献。