大剂量甲苯咪唑作为罗阿丝虫病患者微丝蚴杀虫剂的疗效不佳。
Failure of high dose mebendazole as a microfilaricide in patients with loiasis.
作者信息
Burchard G D, Kern P
机构信息
Laboratoire de Recherches, Albert Schweitzer Hospital, Lambarene, Gabon.
出版信息
Trans R Soc Trop Med Hyg. 1987;81(3):420. doi: 10.1016/0035-9203(87)90156-8.
PMID:3318018
Abstract
The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied. The drug regimen was 1 g twice daily for 21 days in adults. During and after treatment, the microfilarial density was unchanged. Therefore, mebendazole has no direct effect on the microfilarial density of Loa loa.
摘要
研究了甲苯达唑对罗阿丝虫病患者作为杀微丝蚴剂的有效性。成人的给药方案为每日2次，每次1g，共21天。治疗期间及治疗后，微丝蚴密度无变化。因此，甲苯达唑对罗阿丝虫的微丝蚴密度无直接影响。
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